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Anti-CD133 Antibody (7E664)

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货号 TMAB-03840

Anti-CD133 Antibody (7E664) 是一种 Rabbit 抗体,靶向 CD133。Anti-CD133 Antibody (7E664) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-CD133 Antibody (7E664)

Anti-CD133 Antibody (7E664)

一键复制产品信息
Rating icon 还可以
货号 TMAB-03840

Anti-CD133 Antibody (7E664) 是一种 Rabbit 抗体,靶向 CD133。Anti-CD133 Antibody (7E664) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍


生物活性
产品描述
Anti-CD133 Antibody (7E664) is a Rabbit antibody targeting CD133. Anti-CD133 Antibody (7E664) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
7E664
反应种属
Human
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:1000-5000; IHC-P: 1:200-1000; IHC-Fr: 1:200-1000; IF: 1:200-1000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cell projection, cilium, photoreceptor outer segment. Isoform 1: Apical cell membrane; Multi-pass membrane protein. Cell projection, microvillus membrane; Multi-pass membrane protein. Note=Found in extracellular membrane particles in various body fluids such as cerebrospinal fluid, saliva, seminal fluid and urine.
组织特异性Isoform 1 is selectively expressed on CD34 hematopoietic stem and progenitor cells in adult and fetal bone marrow, fetal liver, cord blood and adult peripheral blood. Isoform 1 is not detected on other blood cells. Isoform 1 is also expressed in a number of non-lymphoid tissues including retina, pancreas, placenta, kidney, liver, lung, brain and heart. Found in saliva within small membrane particles. Isoform 2 is predominantly expressed in fetal liver, skeletal muscle, kidney, and heart as well as adult pancreas, kidney, liver, lung, and placenta. Isoform 2 is highly expressed in fetal liver, low in bone marrow, and barely detectable in peripheral blood. Isoform 2 is expressed on hematopoietic stem cells and in epidermal basal cells (at protein level). Expressed in adult retina by rod and cone photoreceptor cells (at protein level).
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.
抗原信息
免疫原
A synthesized peptide: human CD133
抗原种属
Human
基因名称
PROM1
基因ID
蛋白名称
Prominin-1
Uniprot ID
功能
Binds cholesterol in cholesterol-containing plasma membrane microdomains. Proposed to play a role in apical plasma membrane organization of epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.
化学信息
分子量Theoretical: 97 kDa. Actual: 133 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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