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Anti-CXCL10 Antibody (8I302)
还可以产品编号 TMAH-00320
Anti-CXCL10 Antibody (8I302) 是一种抗体，靶向 CXCL10。Anti-CXCL10 Antibody (8I302) 可用于 ELISA, IHC。
Anti-CXCL10 Antibody (8I302)
Anti-CXCL10 Antibody (8I302)
还可以产品编号 TMAH-00320
Anti-CXCL10 Antibody (8I302) 是一种抗体，靶向 CXCL10。Anti-CXCL10 Antibody (8I302) 可用于 ELISA, IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,310 | 5日内发货 | |
| 100 μL | ¥ 2,185 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CXCL10 Antibody (8I302) is an antibody targeting CXCL10. Anti-CXCL10 Antibody (8I302) can be used in ELISA, IHC. |
| Ig Type | Rabbit IgG |
| 克隆号 | 8I302 |
| 交叉反应 | Human |
| 验证活性 | IHC image of TMAH-00320 diluted at 1:100 and staining in paraffin-embedded human ovarian cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
| 应用 | ELISA, IHC |
| 推荐剂量 | IHC:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Secreted. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects. Plays thereby an important role during viral infections by stimulating the activation and migration of immune cells to the infected sites. Mechanistically, binding of CXCL10 to the CXCR3 receptor activates G protein-mediated signaling and results in downstream activation of phospholipase C-dependent pathway, an increase in intracellular calcium production and actin reorganization. In turn, recruitment of activated Th1 lymphocytes occurs at sites of inflammation. Activation of the CXCL10/CXCR3 axis plays also an important role in neurons in response to brain injury for activating microglia, the resident macrophage population of the central nervous system, and directing them to the lesion site. This recruitment is an essential element for neuronal reorganization. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human IP10 |
| 抗原种属 | Human |
| 基因ID | 3627 |
| Uniprot ID | |
| 研究领域 | Cancer, Immunology |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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