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Anti-CD155/PVR Antibody (7L672)
还可以产品编号 TMAH-01026
别名 Tage4, PVSFLJ25946, PVS, PVR, nectin-like 5, Necl-5, NECL5, HVED, FLJ25946, CD155
Anti-CD155/PVR Antibody (7L672) 是一种抗体，靶向 CD155/PVR。Anti-CD155/PVR Antibody (7L672) 可用于 ELISA, WB, IHC。
Anti-CD155/PVR Antibody (7L672)
Anti-CD155/PVR Antibody (7L672)
还可以产品编号 TMAH-01026 别名 Tage4, PVSFLJ25946, PVS, PVR, nectin-like 5, Necl-5, NECL5, HVED, FLJ25946, CD155
Anti-CD155/PVR Antibody (7L672) 是一种抗体，靶向 CD155/PVR。Anti-CD155/PVR Antibody (7L672) 可用于 ELISA, WB, IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,315 | 5日内发货 | |
| 100 μL | ¥ 2,185 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CD155/PVR Antibody (7L672) is an antibody targeting CD155/PVR. Anti-CD155/PVR Antibody (7L672) can be used in ELISA, WB, IHC. |
| 别名 | Tage4, PVSFLJ25946, PVS, PVR, nectin-like 5, Necl-5, NECL5, HVED, FLJ25946, CD155 |
| Ig Type | Rabbit IgG |
| 克隆号 | 7L672 |
| 交叉反应 | Human |
| 验证活性 | 1. Western Blot -Positive WB detected in: A549 whole cell lysate -All lanes: Poliovirus Receptor antibody at 1:500 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 70 kDa -Observed band size: 70 kDa 2. IHC image of TMAH-01026 diluted at 1:50 and staining in paraffin-embedded human lung cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.42% DAB. |
| 应用 | ELISA, WB, IHC |
| 推荐剂量 | WB:1:500-1:2000; IHC:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | [Isoform Alpha]: Cell membrane; Single-pass type I membrane protein.; [Isoform Delta]: Cell membrane; Single-pass type I membrane protein.; [Isoform Beta]: Secreted.; [Isoform Gamma]: Secreted. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytotoxicity of activated NK cells. May also promote NK cell-target cell modular exchange, and PVR transfer to the NK cell. This transfer is more important in some tumor cells expressing a lot of PVR, and may trigger fratricide NK cell activation, providing tumors with a mechanism of immunoevasion. Plays a role in mediating tumor cell invasion and migration. (Microbial infection) Acts as a receptor for poliovirus. May play a role in axonal transport of poliovirus, by targeting virion-PVR-containing endocytic vesicles to the microtubular network through interaction with DYNLT1. This interaction would drive the virus-containing vesicle to the axonal retrograde transport. (Microbial infection) Acts as a receptor for Pseudorabies virus. (Microbial infection) Is prevented to reach cell surface upon infection by Human cytomegalovirus /HHV-5, presumably to escape immune recognition of infected cell by NK cells. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human PVR |
| 抗原种属 | Human |
| 基因ID | 5817 |
| Uniprot ID | |
| 研究领域 | Microbiology |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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