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顶部生物活性储存和溶解信息计算器

Anti-CD155/PVR Antibody (7L672)

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产品编号 TMAH-01026

别名 Tage4, PVSFLJ25946, PVS, PVR, nectin-like 5, Necl-5, NECL5, HVED, FLJ25946, CD155

Anti-CD155/PVR Antibody (7L672) 是一种抗体，靶向 CD155/PVR。Anti-CD155/PVR Antibody (7L672) 可用于 ELISA,IHC,WB。

Anti-CD155/PVR Antibody (7L672)

Anti-CD155/PVR Antibody (7L672)

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产品编号 TMAH-01026 别名 Tage4, PVSFLJ25946, PVS, PVR, nectin-like 5, Necl-5, NECL5, HVED, FLJ25946, CD155

Anti-CD155/PVR Antibody (7L672) 是一种抗体，靶向 CD155/PVR。Anti-CD155/PVR Antibody (7L672) 可用于 ELISA,IHC,WB。

规格价格库存数量
50 μL
¥ 1,315
5日内发货
100 μL
¥ 2,185
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD155/PVR Antibody (7L672) is an antibody targeting CD155/PVR. Anti-CD155/PVR Antibody (7L672) can be used in ELISA,IHC,WB.
别名Tage4, PVSFLJ25946, PVS, PVR, nectin-like 5, Necl-5, NECL5, HVED, FLJ25946, CD155
Ig Type
Rabbit IgG
克隆号
7L672
交叉反应
Human
验证活性
1. Western Blot
-Positive WB detected in: A549 whole cell lysate
-All lanes: Poliovirus Receptor antibody at 1:500
-Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution
-Predicted band size: 70 kDa
-Observed band size: 70 kDa
2. IHC image of TMAH-01026 diluted at 1:50 and staining in paraffin-embedded human lung cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.42% DAB.
应用ELISAIHCWB
推荐剂量
WB:1:500-1:2000; IHC:1:50-1:200.
抗体种类
Monoclonal
亚细胞定位[Isoform Alpha]: Cell membrane; Single-pass type I membrane protein.; [Isoform Delta]: Cell membrane; Single-pass type I membrane protein.; [Isoform Beta]: Secreted.; [Isoform Gamma]: Secreted.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytotoxicity of activated NK cells. May also promote NK cell-target cell modular exchange, and PVR transfer to the NK cell. This transfer is more important in some tumor cells expressing a lot of PVR, and may trigger fratricide NK cell activation, providing tumors with a mechanism of immunoevasion. Plays a role in mediating tumor cell invasion and migration. (Microbial infection) Acts as a receptor for poliovirus. May play a role in axonal transport of poliovirus, by targeting virion-PVR-containing endocytic vesicles to the microtubular network through interaction with DYNLT1. This interaction would drive the virus-containing vesicle to the axonal retrograde transport. (Microbial infection) Acts as a receptor for Pseudorabies virus. (Microbial infection) Is prevented to reach cell surface upon infection by Human cytomegalovirus /HHV-5, presumably to escape immune recognition of infected cell by NK cells.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: Human PVR
抗原种属
Human
基因名称
PVR
基因ID
5817
Uniprot ID
P15151
研究领域
Microbiology
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

PVSFLJ-25946PVSFLJ 25946NECL-5NECL 5FLJ-25946FLJ 25946CD-155CD 155

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