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顶部产品介绍化学信息储存和溶解信息计算器技术支持

Beta Klotho Protein, Mouse, Recombinant (His)

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Rating icon 很棒
SPR兼容缓冲液
货号 TMPK-01150

别名 β-klotho, βKlotho, β Klotho, MGC142213, klotho β like, Klotho β, klotho beta like, Klotho beta, KLB, BKL, beta-klotho, betaKlotho

Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, but diverse roles for Klb are now emerging. Central Klb expression is low but discrete and may govern FGF-targeted sites. Beta Klotho Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 109.91 kDa and the accession number is Q99N32-1.

Beta Klotho Protein, Mouse, Recombinant (His)
其他形式的 “Beta Klotho Protein, Mouse, Recombinant (His)”:
Beta Klotho Protein, Human, Recombinant (His)
Beta Klotho Protein, Human, Recombinant (aa 53-983, His)

Beta Klotho Protein, Mouse, Recombinant (His)

一键复制产品信息
Rating icon 很棒
SPR兼容缓冲液
货号 TMPK-01150 别名 β-klotho, βKlotho, β Klotho, MGC142213, klotho β like, Klotho β, klotho beta like, Klotho beta, KLB, BKL, beta-klotho, betaKlotho

Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, but diverse roles for Klb are now emerging. Central Klb expression is low but discrete and may govern FGF-targeted sites. Beta Klotho Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 109.91 kDa and the accession number is Q99N32-1.

规格价格库存数量
5 μg
¥ 373
3日内发货
10 μg
¥ 598
3日内发货
20 μg
¥ 983
3日内发货
50 μg
¥ 1,930
3日内发货
100 μg
¥ 3,250
现货
200 μg
¥ 5,890
5日内发货
500 μg
¥ 13,000
5日内发货
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实验操作小课堂
常见问题解答
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选择批次:
纯度: SDS-PAGE: > 90%; SEC-HPLC: > 90%
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资源下载:
COA重组蛋白用户指南

产品介绍

生物活性
产品描述
Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, but diverse roles for Klb are now emerging. Central Klb expression is low but discrete and may govern FGF-targeted sites. Beta Klotho Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 109.91 kDa and the accession number is Q99N32-1.
生物活性
Human FGFR4, hFc Tag captured on CM5 Chip via Protein A can bind Mouse Beta Klotho, His Tag with an affinity constant of 36.97 nM as determined in SPR assay.
研究背景
Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, but diverse roles for Klb are now emerging. Central Klb expression is low but discrete and may govern FGF-targeted sites.
种属
Mouse
表达系统
HEK293 Cells
标签C-His
蛋白编号Q99N32-1
蛋白构建Phe53-Pro994
蛋白纯度
> 90% as determined by Tris-Bis PAGE; > 90% as determined by HPLC
蛋白性状Solution
缓冲液Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
别名β-klotho, βKlotho, β Klotho, MGC142213, klotho β like, Klotho β, klotho beta like, Klotho beta, KLB, BKL, beta-klotho, betaKlotho
内毒素< 1 EU/μg by the LAL method.
化学信息
分子量109.91 kDa (predicted). Due to glycosylation, the protein migrates to 120-130 kDa based on Tris-Bis PAGE result.
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.

计算器

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  • 重组蛋白稀释 计算器
  • 比活力 计算器

剂量转换

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.

关键词

MGC-142213MGC 142213klotho b likeKlotho bb-klothobKlotho
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