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Anti-NAALADL1 Antibody (1Q881)

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产品编号 TMAY-01699

Anti-NAALADL1 Antibody (1Q881) 是一种 Rabbit 抗体,靶向 NAALADL1。Anti-NAALADL1 Antibody (1Q881) 可用于 WB,ELISA。

Anti-NAALADL1 Antibody (1Q881)

Anti-NAALADL1 Antibody (1Q881)

Rating icon 还可以
产品编号 TMAY-01699

Anti-NAALADL1 Antibody (1Q881) 是一种 Rabbit 抗体,靶向 NAALADL1。Anti-NAALADL1 Antibody (1Q881) 可用于 WB,ELISA。

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产品介绍

生物活性
产品描述
Anti-NAALADL1 Antibody (1Q881) is a Rabbit antibody targeting NAALADL1. Anti-NAALADL1 Antibody (1Q881) can be used in WB,ELISA.
Ig Type
Monoclonal Rabbit IgG
克隆号
1Q881
交叉反应
Human
验证活性
Anti-NAALADL1 rabbit monoclonal antibody at 1:500 dilution.

-Lane A: 293T Whole Cell lysate.

-Lysates/proteins at 30 μg per lane.

-Secondary

-Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.

-Developed using the Odyssey technique.

-Performed under reducing conditions.

-Predicted band size:81 kDa.

-Observed band size:100 kDa
应用
WB,ELISA
推荐剂量
WB: 1:500-1:1000; ELISA: 1:25000-1:50000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human NAALADL1 (rh NAALADL1; TMPY-01215; NP_005459.2; Pro 29-Leu 740).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景N-acetylated-alpha-linked acidic dipeptidase-like protein, also known as NAALADL1, NAALADase L, and Ileal dipeptidyl-peptidase, is a Single-pass type II membrane protein and a member of the peptidase M28 family and M28B subfamily. NAALADase L is mainly expressed in the distal small intestine. It is also expressed in the spleen and testis and Weakly expressed in the brain, locating mainly to the brain stem, amygdala, thalamus, and ventral striatum. NAALADase L is a chloride-activated, membrane-bound, metallopeptidase that cleaves the endogenous neuropeptide N-acetyl-aspartyl-glutamate (NAAG). NAAG acts as a partial NMDA agonist as well as a full agonist at the presynaptic metabotropic glutamate receptor 3 (mGluR3), where it acts to reduce glutamate release. NAALADase L also exhibits a dipeptidyl-peptidase IV type activity. NAALADase inhibition may be a novel therapeutic approach to reduce or inhibit heightened aggressiveness, and possibly to treat aggressive behavior associated with psychiatric disorders.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human NAALADL1 protein (TMPY-01215)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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