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Anti-KMT5A/SETD8/PR-Set7 Antibody (7F234) 是一种 Rabbit 抗体,靶向 KMT5A/SETD8/PR-Set7。Anti-KMT5A/SETD8/PR-Set7 Antibody (7F234) 可用于 WB,FCM。
Anti-KMT5A/SETD8/PR-Set7 Antibody (7F234) 是一种 Rabbit 抗体,靶向 KMT5A/SETD8/PR-Set7。Anti-KMT5A/SETD8/PR-Set7 Antibody (7F234) 可用于 WB,FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,480 | 5日内发货 |
产品描述 | Anti-KMT5A/SETD8/PR-Set7 Antibody (7F234) is a Rabbit antibody targeting KMT5A/SETD8/PR-Set7. Anti-KMT5A/SETD8/PR-Set7 Antibody (7F234) can be used in WB,FCM. |
别名 | SET8, SET07, SET domain containing (lysine methyltransferase) 8, PR-Set7, KMT5A |
Ig Type | IgG |
交叉反应 | Human,Mouse |
验证活性 | 1. Western blot analysis of KMT5A on different lysates using anti-KMT5A antibody at 1/1,000 dilution. Positive control: Lane 1: Mouse kidney, Lane 2: Mouse liver, Lane 3: 293T, Lane 4: 293. 2. Flow cytometric analysis of 293T cells with KMT5A antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). |
应用 | |
推荐剂量 | WB: 1:500-2000; FCM: 1:50-100 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. All monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions , benef playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contribute to the maintenance of proper higher order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones. Mediates monomethylation of p53 / TP53 at 'Lys-382', leading to repress p53 / TP53-target genes. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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