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Anti-SPTAN1 Antibody (8O990) 是一种 Rabbit 抗体,靶向 SPTAN1。Anti-SPTAN1 Antibody (8O990) 可用于 WB,IHC。
Anti-SPTAN1 Antibody (8O990) 是一种 Rabbit 抗体,靶向 SPTAN1。Anti-SPTAN1 Antibody (8O990) 可用于 WB,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,495 | 5日内发货 |
产品描述 | Anti-SPTAN1 Antibody (8O990) is a Rabbit antibody targeting SPTAN1. Anti-SPTAN1 Antibody (8O990) can be used in WB,IHC. |
别名 | SPTAN1, SPTA2, Spectrin, non-erythroid alpha subunit, Spectrin alpha chain, non-erythrocytic 1, non-erythrocytic 1, NEAS, Fodrin alpha chain, Alpha-II spectrin |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of Alpha Fodrin on different lysates using anti-Alpha Fodrin antibody at 1/500 dilution.Positive control:Lane 1: Hela, Lane 2: Jurkat, Lane 3: NIH-3T3, Lane 4:Rat brain, Lane 5:Mouse brain. 2. Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-Alpha Fodrin antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-Alpha Fodrin antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue using anti-Alpha Fodrin antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | WB: 1:500-2000; IHC: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Alpha Fodrin also named Spectrin. Spectrin, an actin binding protein that is a major component of the cytoskeletal superstructure of the erythrocyte plasma membrane, is essential in determining the properties of the membrane including its shape and deformability. Spectrins function as membrane organizers and stabilizers, composed of nonhomologous α and β chains, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers. Spectrin α I and spectrin β I are present in erythrocytes, whereas spectrin α II (also designated fodrin α) and spectrin β II (also designated fodrin β) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Activation of calpain results in the breakdown of spectrin α II, a neuronal cytoskeleton protein. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 285/150 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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