购物车
- 全部删除
- 您的购物车当前为空
Anti-CD21 Antibody (7G991) 是一种 Mouse 抗体,靶向 CD21。Anti-CD21 Antibody (7G991) 可用于 IHC-P。
Anti-CD21 Antibody (7G991) 是一种 Mouse 抗体,靶向 CD21。Anti-CD21 Antibody (7G991) 可用于 IHC-P。
产品描述 | Anti-CD21 Antibody (7G991) is a Mouse antibody targeting CD21. Anti-CD21 Antibody (7G991) can be used in IHC-P. |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 7G991 |
交叉反应 | Human, Cynomolgus, Ferret |
验证活性 | 1. Immunochemical staining CD21 in human tonsil with mouse monoclonal antibody at 1:60 dilution, formalin-fixed paraffin embedded sections. 2. Immunochemical staining CD21 in human appendix with mouse monoclonal antibody at 1:60 dilution, formalin-fixed paraffin embedded sections. 3. Immunochemical staining CD21 in cynomolgus spleen with mouse monoclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections. 4. Immunochemical staining CD21 in cynomolgus lymph node with mouse monoclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections. 5. Immunochemical staining CD21 in Ferret spleen with mouse monoclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections. |
应用 | IHC-P |
推荐剂量 | IHC-P: 1:30-1:1000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD21 (rh CD21; P20023-1Met1-Arg971). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD21, also known as Complement component (3d / Epstein Barr virus) receptor 2 and CR2, is a member of the CD system and is a protein involved in complement system. CD21 is present on all mature B-cells and some T-cells and follicular dendritic cells. CD21 on mature B-cells form a complex called the B cell receptor complex with two other membrane proteins, CD19 and CD81. CD21 has a function in the complement system through serving as the cellular receptor specific for ligands such as C3 and C4 which can be attached to foreign macromolecules in order to remove or uptake them. This results in B-cells having enhanced response to the antigen. |
偶联 | Unconjugated |
免疫原 | Recombinant Human CD21 Protein |
抗原种属 | Human |
研究领域 | Serine Proteases and Regulators |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
评论内容