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Anti-Phospho-MAP2K3 (Thr222) Polyclonal Antibody 2

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Anti-Phospho-MAP2K3 (Thr222) Polyclonal Antibody 2
产品编号 TMAC-02455
别名 zMKK 3, SKK2, Protein kinase mitogen activated kinase 3, PRKMK3, PRKMK 3, p-MKK3/6 (Thr222), p-MKK3/6 (T222), MPK 3, MP2K6, MP2K3, mMKK3b, mMKK 3b, MKK3/6 (p-Thr222), MKK3/6 (p-T222), MKK3, MKK 3, Mitogen activated protein kinase kinase 3, MEK3, MEK 3, MAPKK3, MAPKK 3, MAPK kinase 3, MAPK ERK kinase 3, MAP2K 3, MAP kinase kinase 3, MAP Kinase Kinase 3, ERK kinase 3, Dual specificity mitogen activated protein kinase kinase 3

Anti-Phospho-MAP2K3 (Thr222) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-MAP2K3 (Thr222)。Anti-Phospho-MAP2K3 (Thr222) Polyclonal Antibody 可用于 WB,IHC。

Anti-Phospho-MAP2K3 (Thr222) Polyclonal Antibody 2

Anti-Phospho-MAP2K3 (Thr222) Polyclonal Antibody 2

Rating icon 还可以
Anti-Phospho-MAP2K3 (Thr222) Polyclonal Antibody 2
产品编号 TMAC-02455 别名 zMKK 3, SKK2, Protein kinase mitogen activated kinase 3, PRKMK3, PRKMK 3, p-MKK3/6 (Thr222), p-MKK3/6 (T222), MPK 3, MP2K6, MP2K3, mMKK3b, mMKK 3b, MKK3/6 (p-Thr222), MKK3/6 (p-T222), MKK3, MKK 3, Mitogen activated protein kinase kinase 3, MEK3, MEK 3, MAPKK3, MAPKK 3, MAPK kinase 3, MAPK ERK kinase 3, MAP2K 3, MAP kinase kinase 3, MAP Kinase Kinase 3, ERK kinase 3, Dual specificity mitogen activated protein kinase kinase 3

Anti-Phospho-MAP2K3 (Thr222) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-MAP2K3 (Thr222)。Anti-Phospho-MAP2K3 (Thr222) Polyclonal Antibody 可用于 WB,IHC。

规格价格库存数量
50 μL
¥ 1,485
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100 μL
¥ 2,230
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-MAP2K3 (Thr222) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MAP2K3 (Thr222). Anti-Phospho-MAP2K3 (Thr222) Polyclonal Antibody can be used in WB,IHC.
别名zMKK 3, SKK2, Protein kinase mitogen activated kinase 3, PRKMK3, PRKMK 3, p-MKK3/6 (Thr222), p-MKK3/6 (T222), MPK 3, MP2K6, MP2K3, mMKK3b, mMKK 3b, MKK3/6 (p-Thr222), MKK3/6 (p-T222), MKK3, MKK 3, Mitogen activated protein kinase kinase 3, MEK3, MEK 3, MAPKK3, MAPKK 3, MAPK kinase 3, MAPK ERK kinase 3, MAP2K 3, MAP kinase kinase 3, MAP Kinase Kinase 3, ERK kinase 3, Dual specificity mitogen activated protein kinase kinase 3
Ig Type
IgG
交叉反应
Human
验证活性
1. Western blot analysis of extracts from Jurkat cells treated with serum using MAP2K3 (Phospho-Thr222) Antibody TMAC-02455. The lane on the right is treated with the antigen-specific peptide.
2. Immunohistochemical analysis of paraffin-embedded human brain tissue using MAP2K3 (Phospho-Thr222) antibody TMAC-02455 (left) or the same antibody preincubated with blocking peptide (right).
应用
WB
IHC
推荐剂量
WB: 1:500-1000; IHC: 1:50-100
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of threonine 222(A-K-T(p)-M-D) derived from Human MAP2K3
抗原种属
human
Uniprot ID
P46734
化学信息
分子量Actual: 39 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

pMKK3/6 (Thr222)pMKK3/6 (T222)MKK3/6 (pThr222)MKK3/6 (pT222)MKK3/6 (phospho-Thr222)MKK3/6 (phospho-T222)

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