Name: NKG2D/CD314 Protein, Rhesus, Recombinant (aa 78-216, His)
Brand: TargetMol
SKU: TMPY-03376
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 429

3日内发货

10 μg

¥ 697

3日内发货

20 μg

¥ 1,150

3日内发货

50 μg

¥ 2,260

3日内发货

100 μg

¥ 3,820

现货

200 μg

¥ 6,530

5日内发货

500 μg

¥ 13,200

5日内发货

生物活性

产品描述	NKG2D/CD314 Protein, Rhesus, Recombinant (aa 78-216, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 18.3 kDa and the accession number is P61252.
生物活性	1. Immobilized Rhesus His-NKG2D (78-216) at 10 μg/ml (100 μl/well) can bind human ULBP1-Fch , The EC50 of human ULBP1-Fch is 0.12-0.28 μg/ml. 2. Immobilized Rhesus His-NKG2D (78-216) at 10 μg/ml (100 μl/well) can bind human MICB-Fch , The EC50 of human MICB-Fch is 33.8-79 ng/ml.
研究背景	KLRK1 (Killer Cell Lectin Like Receptor K1) is a Protein Coding gene. NKG2D, also known as CD314, is an immune receptor that consists of two disulfide-linked type II transmembrane proteins with short intracellular proteins incapable to transduce signals. To transduce signals, NKG2D needs adaptor proteins and it uses two adaptor proteins, DAP10 and DAP12. These two adaptor proteins associate as homodimers to NKG2D- therefore the entire receptor complex appears as a hexamer. NKG2D can send co-stimulatory signals to activate CD8 T cells. NKG2D also plays an important role in viral control. Cellular stress can induce ligands for NKG2D which results in the cell susceptible to NK cell-mediated lysis.
种属	Rhesus
表达系统	Baculovirus Insect Cells
标签	N-His
蛋白编号	P61252
蛋白构建	A DNA sequence encoding the rhesus NKG2D (NP_001028061.1) (Phe78-Val216) was expressed with a polyhistide tag at the N-terminus. Predicted N terminal: His
蛋白纯度	> 95 % as determined by SDS-PAGE
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris, 500 mM NaCl, 10% glycerol, pH 8.0.Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	Reconstituted with sterile deionized water to 0.15 mg/mL. Reconstitution conditions may vary depending on the lot.
别名	NKG2-D, NKG2D, KLRK1, killer cell lectin-like receptor subfamily K, member 1
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.