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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-MTA3 Polyclonal Antibody

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货号 TMAB-09053

Anti-MTA3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 MTA3。Anti-MTA3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-MTA3 Polyclonal Antibody

Anti-MTA3 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-09053

Anti-MTA3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 MTA3。Anti-MTA3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-MTA3 Polyclonal Antibody is a Rabbit antibody targeting MTA3. Anti-MTA3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Dog,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Metastasis-associated protein 3 (MTA3) is a subunit of the Mi-2/NuRD transcriptional corepressor complex. MTA3 and the Mi-2/NuRD complex mediate repression of Snail in breast cancer cells where MTA3 works to maintain a differentiated, epithelial status. The protein is involved in gene expression regulation by covalent modifications of histone proteins. There are two known isoforms of MTA3, a short and a long form. The short isoform binds to ER and sequesters it to the cytoplasm and betters non-genomic responses, whereas the long form is found in the nucleus. MTA3 is widely expressed in with highest expression in brain, adrenal glands, ovaries and virgin mammary glands. It has been found to be expressed in higher levels in tumors than in adjacent normal tissue in the same individual.
抗原信息
免疫原
KLH conjugated synthetic peptide: human MTA3
抗原种属
Human
基因名称
MTA3
基因ID
57504
蛋白名称
Metastasis-associated protein MTA3
Uniprot ID
Q9BTC8
功能
Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels.
化学信息
分子量Theoretical: 67 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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