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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PR3 Antibody (9Q316)

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货号 TMAB-11705

Anti-PR3 Antibody (9Q316) 是一种 Rabbit 抗体，靶向 PR3。Anti-PR3 Antibody (9Q316) 可用于 IHC-P,IHC-Fr,IF。

Anti-PR3 Antibody (9Q316)

Anti-PR3 Antibody (9Q316)

一键复制产品信息
Rating icon 还可以
货号 TMAB-11705

Anti-PR3 Antibody (9Q316) 是一种 Rabbit 抗体，靶向 PR3。Anti-PR3 Antibody (9Q316) 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-PR3 Antibody (9Q316) is a Rabbit antibody targeting PR3. Anti-PR3 Antibody (9Q316) can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
9Q316
反应种属
Human
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The major features of Wegener granulomatosis are necrotizing granulomatous lesions, which most often affect the upper and lower airways and are associated with vasculitis, necrotizing glomerulonephritis and pulmonary capillaritis. The antigen responsible for this disease is Proteinase 3 (PR3, P29 or myeloblastin), which is one of the antibiotic proteins of neutrophilic granules belonging to the serine protease family. It is closely related to two others: Neutrophil Elastase and azurocidin. All three genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation. PR3 is a neutrophil protein which is able to cleave elastin and is involved in proliferation of human leukemia cells. PR3 is expressed specifically in immature myeloid cells and is a G-CSF-responsive protein critical to factor-independent growth. The genes for all three of the related serine protease family members are located in a cluster on the tip of the short arm of human chromosome 19.
抗原信息
免疫原
Recombinant Protein: human PR3 Protein
抗原种属
Human
基因名称
PRTN3
基因ID
5657
蛋白名称
Myeloblastin
Uniprot ID
P24158
功能
Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.
化学信息
分子量Theoretical: 28 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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