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ALDH1A3 Protein, Human, Recombinant (His)

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产品编号 TMPY-01899

ALDH1A3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 57 kDa and the accession number is A0A024RC95.

ALDH1A3 Protein, Human, Recombinant (His)

一键复制产品信息

产品编号 TMPY-01899

ALDH1A3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 57 kDa and the accession number is A0A024RC95.

规格	价格	库存
5 μg	¥ 683	6-8日内发货
10 μg	¥ 1,130	6-8日内发货
20 μg	¥ 1,930	5日内发货
50 μg	¥ 4,430	5日内发货

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产品信息

生物活性	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
产品描述	ALDH1A3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 57 kDa and the accession number is A0A024RC95.
种属	Human
表达系统	E. coli
标签	N-His
蛋白编号	P47895
别名	RALDH3,MCOP8,ALDH6,ALDH1A6,aldehyde dehydrogenase 1 family, member A3
蛋白构建	A DNA sequence encoding the human ALDH1A3 (NP_000684.2) (Ala 2-Pro 512) was expressed, with a polyhistide tag at the N-terminus. Predicted N terminal: Met
蛋白纯度	> 96 % as determined by SDS-PAGE
分子量	57 kDa (predicted); 57 kDa (reducing conditions)
内毒素	Please contact us for more information.
蛋白性状	Solution
缓冲液	Supplied as sterile PBS 7.4 10% glycerol 0.2% TWEEN20.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Aldehyde dehydrogenase 1 family, member A3 (ALDH1A3), also known as Retinaldehyde dehydrogenase 3 (RALDH3), which belongs to the aldehyde dehydrogenase family. ALDH1A3 is a novel Cancer stem cell (CSC) marker with potential clinical prognostic applicability, and demonstrates a clear correlation between CSC prevalence and the development of metastatic breast cancer. The retinoic acid (RA) biosynthesis enzyme aldehyde dehydrogenase 1A3 (ALDH1A3) is a putative androgen-responsive gene in human prostate cancer epithelial (LNCaP) cells. The RA biosynthesis enzyme ALDH1A3 is androgen responsive and (ii) DHT up-regulation of ALDH1A3 can increase the oxidation of retinal to RA and indirectly affect RA bioactivity and metabolism.