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ALDH1A3 Protein, Human, Recombinant (His)

ALDH1A3 Protein, Human, Recombinant (His)

产品编号 TMPY-01899
别名: ALDH6, aldehyde dehydrogenase 1 family, member A3, ALDH1A6, RALDH3, MCOP8

ALDH1A3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 57 kDa and the accession number is A0A024RC95.

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ALDH1A3 Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
50 μg ¥ 3,820 5日内发货
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产品目录号及名称: ALDH1A3 Protein, Human, Recombinant (His) (TMPY-01899)
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生物活性 Testing in progress
产品描述 ALDH1A3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 57 kDa and the accession number is A0A024RC95.
种属 Human
表达系统 E. coli
标签 N-His
蛋白编号 A0A024RC95
别名 ALDH6, aldehyde dehydrogenase 1 family, member A3, ALDH1A6, RALDH3, MCOP8
蛋白构建 The Human ALDH1A3 (NP_000684.2) (Ala 2-Pro 512) was expressed, with a polyhistide tag at the N-terminus.
蛋白纯度 > 96 % as determined by SDS-PAGE
分子量 57 kDa (predicted)
内毒素 Please contact us for more information.
缓冲液 Supplied as sterile PBS 7.4 10% glycerol 0.2% TWEEN20.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store the product under sterile conditions at -20℃ to -80℃. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Aldehyde dehydrogenase 1 family, member A3 (ALDH1A3), also known as Retinaldehyde dehydrogenase 3 (RALDH3), which belongs to the aldehyde dehydrogenase family. ALDH1A3 is a novel Cancer stem cell (CSC) marker with potential clinical prognostic applicability, and demonstrates a clear correlation between CSC prevalence and the development of metastatic breast cancer. The retinoic acid (RA) biosynthesis enzyme aldehyde dehydrogenase 1A3 (ALDH1A3) is a putative androgen-responsive gene in human prostate cancer epithelial (LNCaP) cells. The RA biosynthesis enzyme ALDH1A3 is androgen responsive and (ii) DHT up-regulation of ALDH1A3 can increase the oxidation of retinal to RA and indirectly affect RA bioactivity and metabolism.

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Keywords

ALDH1A3 Protein, Human, Recombinant (His) ALDH 6 ALDH6 ALDH-6 MCOP 8 aldehyde dehydrogenase 1 family, member A3 RALDH-3 ALDH1A6 RALDH3 MCOP8 RALDH 3 MCOP-8 recombinant recombinant-proteins proteins protein

 

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