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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ASPP2 Antibody (4J964)

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货号 TMAB-02878

Anti-ASPP2 Antibody (4J964) 是一种 Rabbit 抗体，靶向 ASPP2。Anti-ASPP2 Antibody (4J964) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

Anti-ASPP2 Antibody (4J964)

Anti-ASPP2 Antibody (4J964)

一键复制产品信息
Rating icon 还可以
货号 TMAB-02878

Anti-ASPP2 Antibody (4J964) 是一种 Rabbit 抗体，靶向 ASPP2。Anti-ASPP2 Antibody (4J964) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-ASPP2 Antibody (4J964) is a Rabbit antibody targeting ASPP2. Anti-ASPP2 Antibody (4J964) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Ig Type
IgG
克隆号
4J964
反应种属
Human,Rat,Mouse
应用WBIHC-PIHC-FrICC/IFIFFCM
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; ICC/IF: 1:50-200; IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm, perinuclear region. Nucleus. Note=Predominantly found in the perinuclear region. Some small fraction is nuclear. Sequester in the cytoplasm on overexpression of DDX42.
组织特异性Widely expressed. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocyte. Reduced expression in breast carcinomas expressing a wild-type TP53 protein. Overexpressed in lung cancer cell lines.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.
抗原信息
免疫原
A synthesized peptide: human TP53BP2
抗原种属
Human
基因名称
TP53BP2
基因ID
7159
蛋白名称
Apoptosis-stimulating of p53 protein 2
Uniprot ID
Q13625
功能
Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.
化学信息
分子量Theoretical: 126 kDa. Actual: 150 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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