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Anti-Neurofascin Antibody-PE (9U713) 是一种 PE-conjugated Mouse 抗体,靶向 Neurofascin。Anti-Neurofascin Antibody-PE (9U713) 可用于 FCM。
Anti-Neurofascin Antibody-PE (9U713) 是一种 PE-conjugated Mouse 抗体,靶向 Neurofascin。Anti-Neurofascin Antibody-PE (9U713) 可用于 FCM。
产品描述 | Anti-Neurofascin Antibody-PE (9U713) is a PE-conjugated Mouse antibody targeting Neurofascin. Anti-Neurofascin Antibody-PE (9U713) can be used in FCM. |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 9U713 |
交叉反应 | Human |
验证活性 | Flow cytometric analysis of Human NFASC expression on SH-SY5Y cells. Cells were stained with PE-conjugated anti-Human NFASC. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
应用 | FCM |
推荐剂量 | 10 μl/Test, 0.1 mg/ml |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human NFASC / Neurofascin (rh NFASC / Neurofascin; TMPY-03797; O94856-12; Met1-Gln939) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
研究背景 | NFASC (Neurofascin, also known as NRCAML, NEDCPMD, and NF) is a Protein Coding gene. 13 alternatively spliced human isoforms have been reported. NFASC belongs to the immunoglobulin superfamily, L1/neurofascin/NgCAM family. It contains 5 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. NFASC links the AIS extracellular matrix to the intracellular cytoskeleton. It is broadly expressed in the brain, kidney, and other tissues. Diseases associated with NFASC include Neurodevelopmental Disorder With Central And Peripheral Motor Dysfunction and Demyelinating Polyneuropathy. |
偶联 | PE |
免疫原 | Recombinant Human NFASC / Neurofascin protein (TMPY-03797) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
运输方式 | Shipping with blue ice. |
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