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Anti-CD182 Monoclonal Antibody (5S630) 是一种 Mouse 抗体,靶向 CD182。Anti-CD182 Monoclonal Antibody (5S630) 可用于 IHC,IF,FCM。
别名 IL8RB, IL8RA, IL8R2, CXCR2, CMKAR2, CDw128b
Anti-CD182 Monoclonal Antibody (5S630) 是一种 Mouse 抗体,靶向 CD182。Anti-CD182 Monoclonal Antibody (5S630) 可用于 IHC,IF,FCM。

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| 产品描述 | Anti-CD182 Monoclonal Antibody (5S630) is a Mouse antibody targeting CD182. Anti-CD182 Monoclonal Antibody (5S630) can be used in IHC,IF,FCM. |
| 别名 | IL8RB, IL8RA, IL8R2, CXCR2, CMKAR2, CDw128b |
| Ig Type | IgG1 |
| 克隆号 | 5S630 |
| 反应种属 | Human |
| 应用 | IHCIFFCM |
| 推荐剂量 | IHC: 1/200-1/1000; IF: 1/100; FCM: 1/200-1/400 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide |
| 浓度 | 1 mg/ml |
| 研究背景 | The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human CD182 expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | CXCR2 |
| 基因ID | |
| 蛋白名称 | C-X-C chemokine receptor type 2 |
| Uniprot ID |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |