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Anti-CD182 Monoclonal Antibody (5S630)

Synonyms: IL8RB, IL8RA, IL8R2, CXCR2, CMKAR2, CDw128b
货号 TMAT-0301 一键复制产品信息
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Anti-CD182 Monoclonal Antibody (5S630) 是一种 Mouse 抗体,靶向 CD182。Anti-CD182 Monoclonal Antibody (5S630) 可用于 IHC,IF,FCM。

Anti-CD182 Monoclonal Antibody (5S630)

一键复制产品信息
Rating icon 还可以
货号 TMAT-0301

别名 IL8RB, IL8RA, IL8R2, CXCR2, CMKAR2, CDw128b

Anti-CD182 Monoclonal Antibody (5S630) 是一种 Mouse 抗体,靶向 CD182。Anti-CD182 Monoclonal Antibody (5S630) 可用于 IHC,IF,FCM。

Anti-CD182 Monoclonal Antibody (5S630)
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产品介绍


生物活性
产品描述
Anti-CD182 Monoclonal Antibody (5S630) is a Mouse antibody targeting CD182. Anti-CD182 Monoclonal Antibody (5S630) can be used in IHC,IF,FCM.
别名
IL8RB, IL8RA, IL8R2, CXCR2, CMKAR2, CDw128b
Ig Type
IgG1
克隆号
5S630
反应种属
Human
应用IHCIFFCM
推荐剂量
IHC: 1/200-1/1000; IF: 1/100; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/ml
研究背景The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human CD182 expressed in E. Coli.
抗原种属
Human
基因名称
CXCR2
基因ID
蛋白名称
C-X-C chemokine receptor type 2
Uniprot ID
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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