Anti-EGFR Antibody (9Y91)

Name: Anti-EGFR Antibody (9Y91)
Brand: TargetMol
SKU: TMAY-00025
Rating: 4.5 (1 reviews)

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产品编号 TMAY-00025

别名 PIG61, NISBD2, mENA, HER1, ERBB1, ERBB, epidermal growth factor receptor

Anti-EGFR Antibody (9Y91) 是一种 Rabbit 抗体，靶向 EGFR。Anti-EGFR Antibody (9Y91) 可用于 ELISA,ICC/IF。

Anti-EGFR Antibody (9Y91)

还可以

产品编号 TMAY-00025 别名 PIG61, NISBD2, mENA, HER1, ERBB1, ERBB, epidermal growth factor receptor

Anti-EGFR Antibody (9Y91) 是一种 Rabbit 抗体，靶向 EGFR。Anti-EGFR Antibody (9Y91) 可用于 ELISA,ICC/IF。

规格	价格	库存	数量
100 μL	¥ 2,284	5日内发货

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生物活性

产品描述	Anti-EGFR Antibody (9Y91) is a Rabbit antibody targeting EGFR. Anti-EGFR Antibody (9Y91) can be used in ELISA,ICC/IF.
别名	PIG61, NISBD2, mENA, HER1, ERBB1, ERBB, epidermal growth factor receptor
Ig Type	Monoclonal Rabbit IgG
克隆号	9Y91
交叉反应	Human
验证活性	Immunofluorescence staining of EGFR in A431 cells. Cells were fixed with 4% PFA,blocked with 10% serum, and incubated with rabbit anti-human EGFR monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Cytoplasm and Cell membrane.
应用	ELISA,ICC/IF
推荐剂量	ELISA: 1:5000-1:10000; ICC-IF: 1:20-1:100
抗体种类	Monoclonal
宿主来源	Rabbit
构建方式	This antibody was obtained from a rabbit immunized with purified, recombinant Human EGFR / HER1 / ErbB1 (rh EGFR / HER1 / ErbB1; TMPY-00742; NP_005219; Met 1-Ser 645).
纯化方式	Protein A
性状	Liquid
缓冲液	0.2 μm filtered solution in PBS
研究背景	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy

偶联与修饰

偶联	Unconjugated

抗原信息

免疫原	Recombinant Human EGFR / HER1 / ErbB1 protein (TMPY-00742)
抗原种属	Human
研究领域	Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs)

存储&运输

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式	Shipping with blue ice.