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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-N-octanoyl-Ghrelin 28 (Ser26) Polyclonal Antibody

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货号 TMAB-06466

Anti-N-octanoyl-Ghrelin 28 (Ser26) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 N-octanoyl-Ghrelin 28 (Ser26)。Anti-N-octanoyl-Ghrelin 28 (Ser26) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-N-octanoyl-Ghrelin 28 (Ser26) Polyclonal Antibody

Anti-N-octanoyl-Ghrelin 28 (Ser26) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-06466

Anti-N-octanoyl-Ghrelin 28 (Ser26) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 N-octanoyl-Ghrelin 28 (Ser26)。Anti-N-octanoyl-Ghrelin 28 (Ser26) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
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100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-N-octanoyl-Ghrelin 28 (Ser26) Polyclonal Antibody is a Rabbit antibody targeting N-octanoyl-Ghrelin 28 (Ser26). Anti-N-octanoyl-Ghrelin 28 (Ser26) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
组织特异性Highest level in stomach. All forms are found in serum as well. Other tissues compensate for the loss of ghrelin synthesis in the stomach following gastrectomy.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression. [provided by RefSeq, Nov 2014]
抗原信息
免疫原
KLH conjugated synthesised n-octanoyl-peptide: human Ghrelin 28 around the n-octanoyl site of Ser26)
抗原种属
Human
基因名称
GHRL
基因ID
51738
蛋白名称
Appetite-regulating hormone
Uniprot ID
Q9UBU3
功能
Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation. Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility.
化学信息
分子量Theoretical: 3/12 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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