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Anti-IL-32 Antibody (9E288) 是一种 Rabbit 抗体,靶向 IL-32。Anti-IL-32 Antibody (9E288) 可用于 ELISA(Cap)。
Anti-IL-32 Antibody (9E288) 是一种 Rabbit 抗体,靶向 IL-32。Anti-IL-32 Antibody (9E288) 可用于 ELISA(Cap)。
产品描述 | Anti-IL-32 Antibody (9E288) is a Rabbit antibody targeting IL-32. Anti-IL-32 Antibody (9E288) can be used in ELISA(Cap). |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 9E288 |
交叉反应 | Human |
应用 | ELISA(Cap) |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human IL32 (rh IL32; TMPY-01033; NP_001012651.1; Met1-Lys131). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathways. It is regulated robustly by other major proinflammatory cytokines and is crucial to inflammation and immune responses. Four of the IL-32 isoforms (alpha, beta, gamma, and delta) are the most representative IL-32 transcripts, and the gamma isoform of IL-32 is the most active, although all isoforms are biologically active. IL-32, a cytokine produced mainly by T, natural killer, and epithelial cells induces significant amounts of TNFalpha and MIP-2 and increases the production of both cytokines in a dose-dependent manner. IL-32 has been implicated in inflammatory disorders, Mycobacterium tuberculosis infections, inflammatory bowel disease, and influenza A virus infection, as well as in some autoimmune diseases, such as rheumatoid arthritis, ulcerative colitis, and in the human stomach cancer, human lung cancer, and breast cancer tissues. Thus, IL-32 expression might be valuable as a biomarker for cancer. |
偶联 | Unconjugated |
免疫原 | Recombinant Human IL32 Protein (TMPY-01033) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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