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Anti-CXADR/CAR Antibody-FITC (7D440) 是一种 FITC-conjugated Rabbit 抗体,靶向 CXADR/CAR。Anti-CXADR/CAR Antibody-FITC (7D440) 可用于 FCM。
Anti-CXADR/CAR Antibody-FITC (7D440) 是一种 FITC-conjugated Rabbit 抗体,靶向 CXADR/CAR。Anti-CXADR/CAR Antibody-FITC (7D440) 可用于 FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 T | ¥ 890 | 5日内发货 | |
100 T | ¥ 1,790 | 5日内发货 |
产品描述 | Anti-CXADR/CAR Antibody-FITC (7D440) is a FITC-conjugated Rabbit antibody targeting CXADR/CAR. Anti-CXADR/CAR Antibody-FITC (7D440) can be used in FCM. |
别名 | HCAR, CXADR, coxsackie virus and adenovirus receptor, CAR4/6, CAR |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 7D440 |
交叉反应 | Human |
验证活性 | Flow cytometric analysis of human CXADR expression on HT-29 cells. HT-29 cells were stained with FITC-conjugated anti-Human CXARD. The histogram were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
应用 | FCM |
推荐剂量 | 10 μl/Test, 0.1 mg/ml |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CXADR / CAR (rh CXADR / CAR; TMPY-02121; NP_001329.1; Met1-Gly237) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
研究背景 | CXADR (coxsackie virus and adenovirus receptor), also known as CAR, is a type I transmembrane glycoprotein belonging to the CTX family of the Ig superfamily, and is essential for normal cardiac development in the mouse. Proposed as a homophilic cell adhesion molecule, CXADR is a component of the epithelial apical junction complex that is essential for the tight junction integrity, and probably involved in transepithelial migration of polymorphonuclear leukocytes (PMN). Mature mouse CXADR structrually comprises a 218 aa extracellular domain (ECD) with a V-type (D1) and a C2-type (D2) Ig-like domain, a 21 aa transmembrane segment and a 17 aa intracellular domain, among which,D1 is thought to be responsible for homodimer formation in trans within tight junctions. The ECD of mouse CXADR shares 97%, 9% sequence identity with the corresponding regions of rat, human CXADR. |
偶联 | FITC |
其他可选修饰符 | Unconjugated/PE |
可提供抗体种类 | 3 |
免疫原 | Recombinant Human CXADR / CAR protein (TMPY-02121) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
运输方式 | Shipping with blue ice. |
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