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Anti-CD40 Antibody-FITC (9S211)
还可以产品编号 TMAY-01155F
Anti-CD40 Antibody-FITC (9S211) 是一种 FITC-conjugated Mouse 抗体，靶向 CD40。Anti-CD40 Antibody-FITC (9S211) 可用于 FCM。
Anti-CD40 Antibody-FITC (9S211)
Anti-CD40 Antibody-FITC (9S211)
还可以产品编号 TMAY-01155F
Anti-CD40 Antibody-FITC (9S211) 是一种 FITC-conjugated Mouse 抗体，靶向 CD40。Anti-CD40 Antibody-FITC (9S211) 可用于 FCM。
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抗原信息
| 产品描述 | Anti-CD40 Antibody-FITC (9S211) is a FITC-conjugated Mouse antibody targeting CD40. Anti-CD40 Antibody-FITC (9S211) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG2b |
| 克隆号 | 9S211 |
| 交叉反应 | Human |
| 验证活性 | Profile of CD40 reactivity on Daudi cells analyzed by flow cytometry. Cells should be Fc-blocked by treatment with 10 μg of human IgG/106 cells for 1 hour at 4°C prior to staining, washed, then stained with FITC Mouse anti-CD40. |
| 应用 | FCM |
| 推荐剂量 | 10 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD40 / TNFRSF5 (rh CD40 / TNFRSF5; TMPY-01181; NP_001241.1; Met 1-Arg 193) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| 研究背景 | CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 protein is expressed in B cells, dendritic cells, macrophages, endothelial cells, and several tumor cell lines. Defects in CD40 result in hyper-IgM immunodeficiency type 3 (HIGM3). In addition, CD40/CD40L interaction is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| 偶联 | FITC |
| 其他可选修饰符 | Unconjugated/APC/PE |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human CD40 protein (TMPY-01181) |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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