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Anti-S100A11 Antibody (4C515) 是一种 Rabbit 抗体,靶向 S100A11。Anti-S100A11 Antibody (4C515) 可用于 ELISA。
Anti-S100A11 Antibody (4C515) 是一种 Rabbit 抗体,靶向 S100A11。Anti-S100A11 Antibody (4C515) 可用于 ELISA。
产品描述 | Anti-S100A11 Antibody (4C515) is a Rabbit antibody targeting S100A11. Anti-S100A11 Antibody (4C515) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 4C515 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human S100A11 / S100C (rh S100A11 / S100C; TMPY-01331; NP_005611.1; Met1-Thr105). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Protein S100-A11, also known as S100 calcium-binding protein A11, S100A11 and MLN70, is a member of theS-100 family. S100A11 is widely expressed in multiple tissues, and is located in cytoplasm, nucleus, and even cell periphery. S100A11 exists as a non-covalent homodimer with an antiparallel conformation. Ca(2+) binding to S100A11 would trigger conformational changes which would expose the hydrophobic cleft of S100A11 and facilitate its interaction with target proteins. As a dual cell growth mediator, S100A11 acts as either a tumor suppressor or promoter in many different types of tumors and would play respective roles in influencing the proliferation of the cancer cells. In the nucleus, S100A11 suppresses the growth of keratinocytes through p21 (CIP1/WAF1) activation and induces cell differentiation. S100A11 is also a novel diagnostic marker in breast carcinoma. |
偶联 | Unconjugated |
免疫原 | Recombinant Human S100A11 / S100C protein (TMPY-01331) |
抗原种属 | Human |
研究领域 | Calcium-binding Proteins and Related Molecules |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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