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CXCL13/BCA-1 Protein, Human, Recombinant (hFc)

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货号 TMPK-00017

别名 SCYB13, BLR1L, BLC, BCA-1, BCA1, ANGIE2, ANGIE

Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice. CXCL13/BCA-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 37.6 kDa and the accession number is O43927.

CXCL13/BCA-1 Protein, Human, Recombinant (hFc)
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CXCL13/BCA-1 Protein, Human, Recombinant

CXCL13/BCA-1 Protein, Human, Recombinant (hFc)

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Rating icon 很棒
货号 TMPK-00017 别名 SCYB13, BLR1L, BLC, BCA-1, BCA1, ANGIE2, ANGIE

Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice. CXCL13/BCA-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 37.6 kDa and the accession number is O43927.

规格价格库存数量
5 μg
¥ 343
现货
10 μg
¥ 549
现货
20 μg
¥ 898
现货
50 μg
¥ 1,760
3日内发货
100 μg
¥ 2,960
现货
200 μg
¥ 5,350
5日内发货
500 μg
¥ 11,800
5日内发货
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纯度: > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
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产品介绍

生物活性
产品描述
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice. CXCL13/BCA-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 37.6 kDa and the accession number is O43927.
生物活性
Immobilized Human CXCL13, hFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Anti-CXCL13 Antibody, hFc Tag with the EC50 of 17.2ng/ml determined by ELISA.
研究背景
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice.
种属
Human
表达系统
HEK293 Cells
标签N-hFc
蛋白编号O43927
蛋白构建Val23-Per109
蛋白纯度
> 95% as determined by Tris-Bis PAGE
蛋白性状Solution
缓冲液Supplied as 0.22 μm filtered solution in 50 mM Tris, 500 mM NaCl (pH 7.4).
别名SCYB13, BLR1L, BLC, BCA-1, BCA1, ANGIE2, ANGIE
内毒素< 1 EU/μg by the LAL method.
化学信息
分子量37.6 kDa (predicted). Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
颜色White
物理性状Lyophilized powder
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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关键词

SCYB-13SCYB 13BCA 1ANGIE-2ANGIE 2
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