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Anti-HNRNPC Antibody (2T80)

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Anti-HNRNPC Antibody (2T80)
产品编号 TMAC-01993
别名 SNRPC, Nuclear ribonucleoprotein particle C2 protein, Nuclear ribonucleoprotein particle C1 protein, MGC131677, MGC117353, MGC105117, MGC104306, Hnrnpc, hnRNP C1/C2, hnRNP C1 / hnRNP C2, HNRNP, Heterogeneous nuclear ribonucleoproteins C1/C2, Heterogeneous nuclear ribonucleoprotein C, C2, C1/C2, C1

Anti-HNRNPC Antibody (2T80) 是一种 Rabbit 抗体,靶向 HNRNPC。Anti-HNRNPC Antibody (2T80) 可用于 WB,ICC/IF,IHC,IP,FCM。

Anti-HNRNPC Antibody (2T80)

Anti-HNRNPC Antibody (2T80)

Rating icon 还可以
Anti-HNRNPC Antibody (2T80)
产品编号 TMAC-01993 别名 SNRPC, Nuclear ribonucleoprotein particle C2 protein, Nuclear ribonucleoprotein particle C1 protein, MGC131677, MGC117353, MGC105117, MGC104306, Hnrnpc, hnRNP C1/C2, hnRNP C1 / hnRNP C2, HNRNP, Heterogeneous nuclear ribonucleoproteins C1/C2, Heterogeneous nuclear ribonucleoprotein C, C2, C1/C2, C1

Anti-HNRNPC Antibody (2T80) 是一种 Rabbit 抗体,靶向 HNRNPC。Anti-HNRNPC Antibody (2T80) 可用于 WB,ICC/IF,IHC,IP,FCM。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-HNRNPC Antibody (2T80) is a Rabbit antibody targeting HNRNPC. Anti-HNRNPC Antibody (2T80) can be used in WB,ICC/IF,IHC,IP,FCM.
别名SNRPC, Nuclear ribonucleoprotein particle C2 protein, Nuclear ribonucleoprotein particle C1 protein, MGC131677, MGC117353, MGC105117, MGC104306, Hnrnpc, hnRNP C1/C2, hnRNP C1 / hnRNP C2, HNRNP, Heterogeneous nuclear ribonucleoproteins C1/C2, Heterogeneous nuclear ribonucleoprotein C, C2, C1/C2, C1
Ig Type
IgG
交叉反应
Human,Mouse,Rat,zebrafish
验证活性
1. Western blot analysis of hnRNP C1+C2 on different lysates using anti-hnRNP C1+C2 antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: MCF-7, Lane 3: HepG2.
2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-hnRNP C1+C2 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-hnRNP C1+C2 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-hnRNP C1+C2 antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded mouse skin tissue using anti-hnRNP C1+C2 antibody. Counter stained with hematoxylin.
6. Immunohistochemical analysis of paraffin-embedded mouse placenta tissue using anti-hnRNP C1+C2 antibody. Counter stained with hematoxylin.
7. ICC staining hnRNP C1+C2 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
8. ICC staining hnRNP C1+C2 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
9. ICC staining hnRNP C1+C2 in B16-F1 (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
10. Flow cytometric analysis of Hela cells with hnRNP C1+C2 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
应用
推荐剂量
WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:100-500; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of polypeptides that contribute to pre-mRNA processing and transport, and also bind heterogeneous nuclear RNA (hnRNA), which are the transcripts produced by RNA polymerase II. hnRNP complexes are the major constituents of the spliceosome and, in particular, the hnRNP A1 protein is one of the major pre-mRNA/mRNA binding proteins and also one of the most abundant proteins in the nucleus. hnRNP A1 and A2/B1 regulate the processing of pre-mRNA by directly antagonizing the association of various splicing factors and by influencing the splice site selection on pre-mRNA. The majority of hnRNP proteins components are localized to the nucleus; however, some shuttle between the nucleus and the cytoplasm. Most hnRNP proteins, in-cluding hnRNP C1 and C2, contain one or more RNA binding domains and are implicated in the processing of pre-mRNA. hnRNPs F and H are largely related factors that preferentially associate with poly(rG) regions on RNA. Isoforms of these proteins are often generated by alternative processing of the pre-mRNA and by posttranslational modifications such as phosphorylation on serines and threonines and methylation of arginines.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
化学信息
分子量Theoretical: 42 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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