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Anti-NR2C2 Polyclonal Antibody

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货号 TMAB-09613

Anti-NR2C2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 NR2C2。Anti-NR2C2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-NR2C2 Polyclonal Antibody

Anti-NR2C2 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-09613

Anti-NR2C2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 NR2C2。Anti-NR2C2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-NR2C2 Polyclonal Antibody is a Rabbit antibody targeting NR2C2. Anti-NR2C2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Dog,Cow,Horse,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Cell membrane. Translocates to the plasma membrane upon calcium binding.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Orphan nuclear receptor that can act as a repressor or activator of transcription. An important repressor of nuclear recptor signaling pathways such as retinoic acid receptor, retinoid X, vitamin D3 receptor, thyroid hormone receptor and estrogen receptor pathways. May regulate gene expression during the late phase of spermatogenesis. Together with NR2C1, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription including that of GATA1. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Plays a fundamental role in early embryonic development and embryonic stem cells. Required for normal spermatogenesis and cerebellum development. Appears to be important for neurodevelopmentally regulated behavior. Activates transcriptional activity of LHCG. Antagonist of PPARA-mediated transactivation.
抗原信息
免疫原
KLH conjugated synthetic peptide: human NR2C2
抗原种属
Human
基因名称
NR2C2
基因ID
蛋白名称
Nuclear receptor subfamily 2 group C member 2
Uniprot ID
功能
Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
化学信息
分子量Theoretical: 65 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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