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Anti-Caspase 14 Antibody (1R621) 是一种 Rabbit 抗体,靶向 Caspase 14。Anti-Caspase 14 Antibody (1R621) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM。
Anti-Caspase 14 Antibody (1R621) 是一种 Rabbit 抗体,靶向 Caspase 14。Anti-Caspase 14 Antibody (1R621) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 780 | 5日内发货 | |
| 50 μL | ¥ 1,390 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
| 产品描述 | Anti-Caspase 14 Antibody (1R621) is a Rabbit antibody targeting Caspase 14. Anti-Caspase 14 Antibody (1R621) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM. |
| Ig Type | IgG |
| 克隆号 | 1R621 |
| 反应种属 | Human (predicted:Mouse,Rat) |
| 应用 | WBIHC-PIHC-FrICC/IFIFIPFCM |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; ICC/IF: 1:50-200; IF: 1:50-200; IP: 1:20-50; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. Nucleus. |
| 组织特异性 | Expressed in keratinocytes of adult skin suprabasal layers (from spinous layers to the stratum granulosum and stratum corneum) (at protein level). Expressed in keratinocytes of hair shaft and sebaceous glands (at protein level). In psoriatic skin only expressed at very low levels. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | Non-apoptotic caspase involved in epidermal differentiation. Is the predominant caspase in epidermal stratum corneum.Seems to play a role in keratinocyte differentiation and is required for cornification. Regulates maturation of the epidermis by proteolytically processing filaggrin.In vitro has a preference for the substrate [WY]-X-X-D motif and is active on the synthetic caspase substrate WEHD-ACF. |
| 免疫原 | A synthesized peptide: human Caspase 14 |
| 抗原种属 | Human |
| 基因名称 | CASP14 |
| 基因ID | |
| 蛋白名称 | Caspase-14 |
| Uniprot ID | |
| 功能 | Believed to be a non-apoptotic caspase which is involved in epidermal differentiation. Seems to play a role in keratinocyte differentiation and cornification. Probably regulates maturation of the epidermis by proteolytically processing filaggrin. |
| 分子量 | Theoretical: 28 kDa. Actual: 28 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |