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别名 SCYLP, peptidylprolyl isomerase B (cyclophilin B), OI9, HEL-S-39, CYP-S1, CYPB
Anti-Cyclophilin B Antibody (1B168) 是一种 Rabbit 抗体,靶向 Cyclophilin B。Anti-Cyclophilin B Antibody (1B168) 可用于 WB。
Anti-Cyclophilin B Antibody (1B168) 是一种 Rabbit 抗体,靶向 Cyclophilin B。Anti-Cyclophilin B Antibody (1B168) 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,490 | 5日内发货 | |
| 100 μL | ¥ 2,490 | 5日内发货 |
| 产品描述 | Anti-Cyclophilin B Antibody (1B168) is a Rabbit antibody targeting Cyclophilin B. Anti-Cyclophilin B Antibody (1B168) can be used in WB. |
| 别名 | SCYLP, peptidylprolyl isomerase B (cyclophilin B), OI9, HEL-S-39, CYP-S1, CYPB |
| Ig Type | IgG |
| 克隆号 | 1B168 |
| 反应种属 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of Cyclophilin B on different lysates using anti-Cyclophilin B antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: HepG2, Lane 3: NIH/3T3. ![]() |
| 应用 | WB |
| 推荐剂量 | WB: 1:1000-5000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | The immunosuppressant cyclosporin A (CsA) forms a trimolecular complex with cyclophilin and calcineurins to inhibit calcineurin phosphatase activity. Cyclophilins are conserved, ubiquitous and abundant cytosolic peptidyl-prolyl cis-trans isomerases that accelerate the isomerization of XaaPro peptide bonds and the refolding of proteins. Human cyclophilin A (CyPA), an intracellular protein of 165 amino acids, is the target of the Cyclosporin A and is encoded by a single unique gene conserved from yeast to humans. CyPA is known for its involvement in T cell differentiation and proliferation and is highly expressed in brain. CyPA is incorporated into the virion of the type 1 human immunodeficiency virus (HIV-1) via a direct interaction with the capsid domain of the viral Gag polyprotein and is crucial for efficient viral replication. Cyclophilin B (CyPB) is a member of the cyclophilin family with specific N- and C-terminal extensions. Unlike CyPA, CyPB has a signal sequence leading to its translocation in the endoplasmic reticulum. CyPB is secreted in biological fluids such as blood or milk and binds to a specific receptor present on the human lymphoblastic cell line Jurkat and on human peripheral blood lymphocytes. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 18 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |