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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-MAPKAPK3 Antibody (5K175)

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货号 TMAY-01057

别名 MK-3, mitogen-activated protein kinase-activated protein kinase 3, MAPKAPK-3, MAPKAP-K3, MAPKAP3, 3PK

Anti-MAPKAPK3 Antibody (5K175) 是一种 Mouse 抗体，靶向 MAPKAPK3。Anti-MAPKAPK3 Antibody (5K175) 可用于 IHC-P。

Anti-MAPKAPK3 Antibody (5K175)

Anti-MAPKAPK3 Antibody (5K175)

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货号 TMAY-01057 别名 MK-3, mitogen-activated protein kinase-activated protein kinase 3, MAPKAPK-3, MAPKAP-K3, MAPKAP3, 3PK

Anti-MAPKAPK3 Antibody (5K175) 是一种 Mouse 抗体，靶向 MAPKAPK3。Anti-MAPKAPK3 Antibody (5K175) 可用于 IHC-P。

规格价格库存数量
100 μL
¥ 1,679
5日内发货
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产品介绍

生物活性
产品描述
Anti-MAPKAPK3 Antibody (5K175) is a Mouse antibody targeting MAPKAPK3. Anti-MAPKAPK3 Antibody (5K175) can be used in IHC-P.
别名MK-3, mitogen-activated protein kinase-activated protein kinase 3, MAPKAPK-3, MAPKAP-K3, MAPKAP3, 3PK
Ig Type
Mouse IgG2a
克隆号
5K175
反应种属
Human
特异性
Human MAPKAPK3
验证活性
Immunochemical staining of human MAPKAPK3 in human skeletal muscle with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections).
应用IHC-P
推荐剂量
IHC-P: 1:50-1:200
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human MAPKAPK3/MK3 (rh MAPKAPK3/MK3; TMPY-04378; NP_004626.1; Met1-Gln382). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景The MAPKAP kinases are a group of MAP kinase substrates that are themselves kinases. In response to activation, the MAP kinases phosphorylate downstream components on a consensus Pro-X-Ser/Thr-Pro motif. Several kinases that contain this motif have been identified and serve as substrates for the ERK and p38 MAP kinases. Mitogen-activated protein (MAP) kinase-activated protein kinase 3, also known as MAPKAPK-3 and 3pK, is a member of the Ser/Thr protein kinase family. It is widely expressed in human tissues, with a higher expression level observed in the heart and skeletal muscle. No expression in the brain. MAPKAPK-3 is unique since it was shown to be activated by three members of the MAPK family, namely extracellular-signal-regulated kinase (ERK), p38, and Jun-N-terminal kinase (JNK). It is highly activated both by mitogens and by stress-inducing agents or proinflammatory cytokines and translocates to the cytoplasm from the nucleus. MAPKAPK-3 is exclusively activated via the classical MAPK cascade, while stress-induced activation of MAPKAPK-3 is mainly mediated by p38, however, the mechanism defining the specificity remains unknown.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human MAPKAPK3/MK3 Protein (TMPY-04378)
抗原种属
Human
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.
存储-20°C for 1 year

计算器

  • 稀释 计算器

关键词

MK3MK 3MAPKAPK3MAPKAPK 3MAPKAP-3MAPKAP 3
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