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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Keratocan Polyclonal Antibody

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货号 TMAB-01019

别名 SLRR2B, KTN, Keratocan, Keratan sulfate proteoglycan keratocan, KERA, CNA2

Anti-Keratocan Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Keratocan。Anti-Keratocan Polyclonal Antibody 可用于 WB。

Anti-Keratocan Polyclonal Antibody

Anti-Keratocan Polyclonal Antibody

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货号 TMAB-01019 别名 SLRR2B, KTN, Keratocan, Keratan sulfate proteoglycan keratocan, KERA, CNA2

Anti-Keratocan Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Keratocan。Anti-Keratocan Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Keratocan Polyclonal Antibody is a Rabbit antibody targeting Keratocan. Anti-Keratocan Polyclonal Antibody can be used in WB.
别名SLRR2B, KTN, Keratocan, Keratan sulfate proteoglycan keratocan, KERA, CNA2
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Sheep)
验证活性
Sample:
Muscle (Mouse) Lysate at 40 μg
Primary: Anti-Keratocan (TMAB-01019) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 38 kDa
Observed band size: 38 kDa
verifiedActivity
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted > extracellular space > extracellular matrix.
组织特异性Cornea. Increased expression in the stroma of keratoconus corneas. Also detected in trachea, and in low levels, in intestine, skeletal muscle, ovary, lung and putamen.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景Small leucine-rich proteoglycans (SLRPs) such as Decorin, Biglycan, Fibromod-ulin, Keratocan, Lumican and Osteoglycin mediate extracellular matrix organization and are binding partners of TGF Beta. The Decorin core protein binds to growth factors, intercellular matrix molecules such as Fibronectin and Throm-bospondin, and to the Decorin endocytosis receptor. Fibromodulin is a collagen-binding keratan sulphate proteoglycan that influences adhesion processes of connective tissue and plays a role in fibrillogenesis by regulating collagen fibril spacing and thickness. Keratocan (KTN) develops corneal transparency and maintains the stromal matrix structure. Keratocan is a secreted protein in the extracellular matrix that binds to keratan sulfate chains. Keratocan is mainly detected in the cornea, but can also be expressed in trachea, intestine, ovary, lung and skeletal muscle. Defects in the gene encoding for Keratocan can cause cornea plana 2 (CNA2), an autosomal recessive disorder where the forward convex curvature of the cornea is flattened.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Keratocan
抗原种属
Human
基因名称
KERA
基因ID
11081
蛋白名称
Keratocan
Uniprot ID
O60938
研究领域
ECM Proteins,Visual system,Other ECM Proteins,Keratin
功能
May be important in developing and maintaining corneal transparency and for the structure of the stromal matrix.
化学信息
分子量Theoretical: 38 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

计算器

  • 稀释 计算器
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