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Anti-Keratocan Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Keratocan。Anti-Keratocan Polyclonal Antibody 可用于 WB。
Anti-Keratocan Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Keratocan。Anti-Keratocan Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,170 | 5日内发货 | |
100 μL | ¥ 1,970 | 5日内发货 | |
200 μL | ¥ 2,785 | 5日内发货 |
产品描述 | Anti-Keratocan Polyclonal Antibody is a Rabbit antibody targeting Keratocan. Anti-Keratocan Polyclonal Antibody can be used in WB. |
Ig Type | IgG |
交叉反应 | Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Sheep) |
验证活性 | Sample: Muscle (Mouse) Lysate at 40 μg Primary: Anti-Keratocan (TMAB-01019) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 38 kDa Observed band size: 38 kDa |
应用 | |
推荐剂量 | WB: 1:500-2000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
亚细胞定位 | Secreted > extracellular space > extracellular matrix. |
构建方式 | Hybridoma Polyclonal Antibody |
纯化方式 | Protein A purified |
性状 | Liquid |
缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
研究背景 | Small leucine-rich proteoglycans (SLRPs) such as Decorin, Biglycan, Fibromod-ulin, Keratocan, Lumican and Osteoglycin mediate extracellular matrix organization and are binding partners of TGF Beta. The Decorin core protein binds to growth factors, intercellular matrix molecules such as Fibronectin and Throm-bospondin, and to the Decorin endocytosis receptor. Fibromodulin is a collagen-binding keratan sulphate proteoglycan that influences adhesion processes of connective tissue and plays a role in fibrillogenesis by regulating collagen fibril spacing and thickness. Keratocan (KTN) develops corneal transparency and maintains the stromal matrix structure. Keratocan is a secreted protein in the extracellular matrix that binds to keratan sulfate chains. Keratocan is mainly detected in the cornea, but can also be expressed in trachea, intestine, ovary, lung and skeletal muscle. Defects in the gene encoding for Keratocan can cause cornea plana 2 (CNA2), an autosomal recessive disorder where the forward convex curvature of the cornea is flattened. |
免疫原 | KLH conjugated synthetic peptide: human Keratocan |
抗原种属 | Human |
基因ID | |
Uniprot ID | |
研究领域 | ECM Proteins,Visual system,Other ECM Proteins,Keratin |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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