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Anti-Noxa Antibody (1A221) 是一种 Rabbit 抗体,靶向 Noxa。Anti-Noxa Antibody (1A221) 可用于 WB,IHC,FCM。
Anti-Noxa Antibody (1A221) 是一种 Rabbit 抗体,靶向 Noxa。Anti-Noxa Antibody (1A221) 可用于 WB,IHC,FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,495 | 5日内发货 | |
100 μL | ¥ 2,490 | 5日内发货 |
产品描述 | Anti-Noxa Antibody (1A221) is a Rabbit antibody targeting Noxa. Anti-Noxa Antibody (1A221) can be used in WB,IHC,FCM. |
别名 | Protein Noxa, PMA-responsive gene, Pmaip1, PMA-induced protein 1, PMA induced protein 1, Phorbol-12-myristate-13-acetate-induced protein 1, Phorbol 12 myristate 13 acetate induced protein 1, NOXA, Immediate-early-response protein APR, Immediate early response protein APR, ATL-derived, APR_HUMAN, APR, Adult T cell leukemia derived PMA responsive |
Ig Type | IgG |
交叉反应 | Human |
验证活性 | 1. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-Noxa antibody. Counter stained with hematoxylin. 2. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Noxa antibody. Counter stained with hematoxylin. 3. Flow cytometric analysis of Jurkat cells with Noxa antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). |
应用 | |
推荐剂量 | WB: 1:500; IHC: 1:50-200; FCM: 1:50 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Members of the Bcl-2 family of proteins interact to regulate programmed cell death (apoptosis) under a broad range of physiological conditions. Bcl-2, Bcl-xL, and several related proteins inhibit apoptosis, whereas other members of the Bcl-2 family, such as Bax and Bak, enhance cell death. NOXA, a pro-apoptotic member of the Bcl-2 family, contains the Bcl-2 homology 3 (BH3) region, but does not contain other BH domains. Murine cells constitutively express NOXA mRNA in small amounts in various organs; X-ray irradiation increases NOXA mRNA and protein expression levels. In human cells, NOXA, alternatively designated PMA-induced protein 1 or APR, displays high expression in the adult T cell leukemia cell line IKD, where it may function as an immediate-early-response gene. The NOXA protein selectively localizes to mitochondria. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 6 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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