购物车
- 全部删除
您的购物车当前为空
Anti-ARID3B Antibody (2L160)
还可以产品编号 TMAY-00132
Anti-ARID3B Antibody (2L160) 是一种 Rabbit 抗体，靶向 ARID3B。Anti-ARID3B Antibody (2L160) 可用于 WB。
Anti-ARID3B Antibody (2L160)
Anti-ARID3B Antibody (2L160)
还可以产品编号 TMAY-00132
Anti-ARID3B Antibody (2L160) 是一种 Rabbit 抗体，靶向 ARID3B。Anti-ARID3B Antibody (2L160) 可用于 WB。
产品信息正在更新中，如果您想购买，请点击大包装&定制按钮.
大包装 & 定制
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-ARID3B Antibody (2L160) is a Rabbit antibody targeting ARID3B. Anti-ARID3B Antibody (2L160) can be used in WB. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 2L160 |
| 交叉反应 | Human |
| 验证活性 | Anti-ARID3B rabbit monoclonal antibody at 1:500 dilution. -Lane A: 293T Whole Cell Lysate. -Lane B: K562 Whole Cell Lysate. -Lane C: HepG2 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:61 kDa. -Observed band size:68 kDa |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the center region of the Human ARID3B. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | ARID3B, a member of the AT-rich interaction domain (ARID) family of proteins, plays an essential role in the survival of neural crest during embryogenesis. ARID3B seems to play a key role in the malignant transformation of neuroblastoma and may serve not only as a marker of malignancy but also as a potential target for cancer therapy of stage IV neuroblastoma for which there is currently no effective treatment available. ARID3B is a DNA binding protein that is overexpressed in neuroblastoma and ovarian cancer. ARID3B has different patterns in normal tissues translate into different roles for ARID3B in carcinomas. ARID3B (AT-rich interaction domain 3) is a member of the family of ARID proteins, which constitutes evolutionarily conserved transcription factors implicated in normal development, differentiation, cell cycle regulation and chromatin remodeling. In addition, ARID3B has been linked to cellular immortalization, epithelial-mesenchymal transition (EMT) and tumorigenesis. Given the emerging role of ARID3B in tumor development, we examined its expression in primary patient-derived breast cancer samples and breast cancer-derived cell lines. ARID3B regulation of direct target genes in the Wnt pathway promotes adhesion of ovarian cancer cells. ARID3A and ARID3B are transcriptional targets of p53, ARID3B play a key role in the expression of pro-apoptotic p53-target genes and apoptosis. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide corresponding to the center region of the Human ARID3B |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-ARID3B Antibody (2L160) | purchase Anti-ARID3B Antibody (2L160) | Anti-ARID3B Antibody (2L160) cost | order Anti-ARID3B Antibody (2L160)
嗨！有任何问题？点我咨询
评论内容