购物车
  • 全部删除
  • TargetMol
    您的购物车当前为空
顶部生物活性储存和溶解信息计算器

Anti-BID Antibody-HRP (1O729)

Rating icon 还可以
Anti-BID Antibody-HRP (1O729)
产品编号 TMAY-00868H
别名 BH3 interacting domain death agonist, AU022477, AI875481, 2700049M22Rik

Anti-BID Antibody-HRP (1O729) 是一种 HRP-conjugated Mouse 抗体，靶向 BID。Anti-BID Antibody-HRP (1O729) 可用于 ELISA。

Anti-BID Antibody-HRP (1O729)
331

Anti-BID Antibody-HRP (1O729)

Rating icon 还可以
Anti-BID Antibody-HRP (1O729)
产品编号 TMAY-00868H 别名 BH3 interacting domain death agonist, AU022477, AI875481, 2700049M22Rik

Anti-BID Antibody-HRP (1O729) 是一种 HRP-conjugated Mouse 抗体，靶向 BID。Anti-BID Antibody-HRP (1O729) 可用于 ELISA。

规格价格库存数量
100 μg
¥ 2,490
5日内发货
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
联系我们获取更多批次信息
资源下载
产品操作手册

产品介绍

生物活性
产品描述
Anti-BID Antibody-HRP (1O729) is a HRP-conjugated Mouse antibody targeting BID. Anti-BID Antibody-HRP (1O729) can be used in ELISA.
别名BH3 interacting domain death agonist, AU022477, AI875481, 2700049M22Rik
Ig Type
Mouse IgG2a
克隆号
1O729
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 0.1-1 μg/ml
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human BID (rh BID; TMPY-02027; P55957-1; Met 1-Asp 195). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography and conjugated with horseradish-peroxidase (HRP).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景The BH3 interacting domain death agonist (BID) is a pro-apoptotic member of the Bcl-2 protein family, which contains only the BH3 domain, and is required for its interaction with the Bcl-2 family proteins and for its pro-death activity. BID is important to cell death mediated by these proteases and thus is the sentinel to protease-mediated death signals. Recent studies further indicate that Bid may be more than just a killer molecule, it could be also involved in the maintenance of genomic stability by engaging at mitosis checkpoint. BID is an integrating key regulator of the intrinsic death pathway that amplifies caspase-dependent and caspase-independent execution of neuronal apoptosis. Therefore pharmacological inhibition of BID provides a promising therapeutic strategy in neurological diseases where programmed cell death is prominent. BID is activated by Caspase 8 in response to Fas/TNF-R1 death receptor activation. Activated BID is translocated to mitochondria and induces cytochrome c release, which in turn activates downstream caspases. BID action has been proposed to involve the mitochondrial re-location of its truncated form, tBid, to facilitate the release of apoptogenic proteins like cytochrome c.
偶联与修饰
偶联
HRP
其他可选修饰符
Unconjugated
可提供抗体种类
2
抗原信息
免疫原
Recombinant Protein: Human BID protein (TMPY-02027)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器

关键词

AU-022477AU 022477AI-875481AI 875481

评论列表

4个月前
5.0
Rating icon 很棒

评论内容

233
Related Tags: buy Anti-BID Antibody-HRP (1O729) | purchase Anti-BID Antibody-HRP (1O729) | Anti-BID Antibody-HRP (1O729) cost | order Anti-BID Antibody-HRP (1O729)