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Anti-hnRNP M1-M4 Polyclonal Antibody

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货号 TMAB-07222

Anti-hnRNP M1-M4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 hnRNP M1-M4。Anti-hnRNP M1-M4 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-hnRNP M1-M4 Polyclonal Antibody

Anti-hnRNP M1-M4 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-07222

Anti-hnRNP M1-M4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 hnRNP M1-M4。Anti-hnRNP M1-M4 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-hnRNP M1-M4 Polyclonal Antibody is a Rabbit antibody targeting hnRNP M1-M4. Anti-hnRNP M1-M4 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Dog,Horse)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus, nucleolus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
抗原信息
免疫原
KLH conjugated synthetic peptide: human hnRNP M1-M4
抗原种属
Human
基因名称
HNRNPM
基因ID
4670
蛋白名称
Heterogeneous nuclear ribonucleoprotein M
Uniprot ID
P52272
功能
Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines.
化学信息
分子量Theoretical: 78 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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