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Anti-CD68 Antibody (4Z963)
还可以产品编号 TMAY-01739
Anti-CD68 Antibody (4Z963) 是一种 Rabbit 抗体，靶向 CD68。Anti-CD68 Antibody (4Z963) 可用于 IHC-P。
Anti-CD68 Antibody (4Z963)
Anti-CD68 Antibody (4Z963)
还可以产品编号 TMAY-01739
Anti-CD68 Antibody (4Z963) 是一种 Rabbit 抗体，靶向 CD68。Anti-CD68 Antibody (4Z963) 可用于 IHC-P。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CD68 Antibody (4Z963) is a Rabbit antibody targeting CD68. Anti-CD68 Antibody (4Z963) can be used in IHC-P. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 4Z963 |
| 交叉反应 | Human, Cynomolgus |
| 验证活性 | 1. Immunochemical staining CD68 in human lung with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining CD68 in human liver with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 3. Immunochemical staining CD68 in cynomolgus lung with rabbit monoclonal antibody at 1:60 dilution, formalin-fixed paraffin embedded sections. |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:60-1:500 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD68 (rh CD68; TMPY-02972; P34810-1; Met1-Ser319). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Macrosialin, also known as CD68 and Gp11, is a single-pass type I membrane protein which belongs to theLAMP family. CD68 is highly expressed by blood monocytes and tissue macrophages. It is also expressed in lymphocytes, fibroblasts and endothelial cells. CD68 is expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites. CD68 plays a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It is a commonly used marker for macrophages. However, a number of studies have shown that CD68 antibodies react with other hematopoietic and non-hematopoietic cell types, suggesting that CD68 may not be a macrophage-specific antigen. CD68 binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human CD68 Protein (TMPY-02972) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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