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顶部生物活性储存和溶解信息计算器

Anti-c-Rel Antibody (9I816)

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产品编号 TMAC-00977

别名 REL, Proto-oncogene c-Rel

Anti-c-Rel Antibody (9I816) 是一种 Rabbit 抗体，靶向 c-Rel。Anti-c-Rel Antibody (9I816) 可用于 IHC,IP,WB。

Anti-c-Rel Antibody (9I816)

Anti-c-Rel Antibody (9I816)

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产品编号 TMAC-00977 别名 REL, Proto-oncogene c-Rel

Anti-c-Rel Antibody (9I816) 是一种 Rabbit 抗体，靶向 c-Rel。Anti-c-Rel Antibody (9I816) 可用于 IHC,IP,WB。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-c-Rel Antibody (9I816) is a Rabbit antibody targeting c-Rel. Anti-c-Rel Antibody (9I816) can be used in IHC,IP,WB.
别名REL, Proto-oncogene c-Rel
Ig Type
IgG
克隆号
9I816
交叉反应
Human
验证活性
1. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-c-Rel antibody. Counter stained with hematoxylin.
2. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-c-Rel antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human skin tissue using anti-c-Rel antibody. Counter stained with hematoxylin.
verifiedActivityverifiedActivityverifiedActivity
应用IHCIPWB
推荐剂量
WB: 1:500; IHC: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景c-Rel is the cellular cognate of v-Rel, the avian reticuloendotheliosis virus strain T transforming gene. v-Rel encodes a phosphoprotein that is located in the cytoplasm of transformed spleen cells and in the nucleus of non-transformed fibroblasts, in contrast to the c-Rel protein, which is cytoplasmic. c-Rel has been shown to represent a constituent of the κB site binding transcription factor NFκB, which plays a crucial role in the expression of immunoglobulin κ light chain gene. In contrast to c-Rel, v-Rel is truncated in its C-terminal transactivation domain and does not appear to function as a transcriptional transactivator. It has thus been postulated that v-Rel may interfere with the normal transcription of NFκB regulated genes and thus cause transformation by a mechanism analogous to v-ErbA, which binds to the thyroid hormone-responsive region in certain erythroid genes needed for differentiation, but cannot be activated by thyroid hormone.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q04864
化学信息
分子量Theoretical: 68 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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