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CD30/TNFRSF8 Protein, Human, Recombinant (His)

CD30/TNFRSF8 Protein, Human, Recombinant (His)

产品编号 TMPY-01827
别名: D1S166E, tumor necrosis factor receptor superfamily, member 8, Ki-1, CD30

CD30/TNFRSF8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P28908-1.

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TargetMol
CD30/TNFRSF8 Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
100 μg ¥ 2,520 现货
200 μg ¥ 4,470 5日内发货
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产品目录号及名称: CD30/TNFRSF8 Protein, Human, Recombinant (His) (TMPY-01827)
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生物活性
技术参数
产品性质
参考文献
生物活性 Immobilized Human CD30L hFc at 2 μg/mL (100 μL/well) can bind Human CD30/TNFRSF8 His, the EC50 of Human CD30/TNFRSF8 His is 30-180 ng/mL.

TargetMol Bioactive

产品描述 CD30/TNFRSF8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P28908-1.
种属 Human
表达系统 HEK293 Cells
标签 C-His
蛋白编号 P28908-1
别名 D1S166E, tumor necrosis factor receptor superfamily, member 8, Ki-1, CD30
蛋白构建 The Human TNFRSF8 (NP_001234.2) extracellular domain (Met 1-Lys 379) was expressed, fused with a polyhistidine tag at the C-terminus.
蛋白纯度 > 95 % as determined by SDS-PAGE

TargetMol

分子量 40 kDa (predicted)
内毒素 < 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of lymphocytes and may also play an important role in human immunodeficiency virus replication. As a regulator of apoptosis, CD30 protein induces cell death or proliferation, depending on the cell type, and has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. CD30 protein expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs), and CD30 is also linked to leukocytes in patients with chronic inflammatory diseases, including lupus erythematosus, asthma, rheumatoid arthritis and atopic dermatitis (AD).Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy

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Keywords

CD30/TNFRSF8 Protein, Human, Recombinant (His) D1S166E CD 30 tumor necrosis factor receptor superfamily, member 8 Ki-1 CD-30 CD30 recombinant recombinant-proteins proteins protein

 

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