Name: KIF18A-IN-3
Brand: TargetMol
SKU: T64068
Price: 2450 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

1 mg

¥ 2,450

现货

5 mg

¥ 5,790

现货

10 mg

¥ 7,790

现货

25 mg

¥ 11,600

现货

1 mL x 10 mM (in DMSO)

¥ 7,760

现货

产品介绍

生物活性

产品描述	KIF18A-IN-3 is an efficient KIF18A inhibitor (IC50 = 61nM) that induces mitotic arrest and increases the number of mitotic cells in tumor tissues. It can be used in tumor research.
靶点活性	KIF18A:61 nM
体外活性	KIF18A-IN-3 是一种有效的 KIF18A 抑制剂其 IC50 = 61 nM。[1]
体内活性	KIF18A-IN-3 （100 mg/kg，ip.）在长达 24 小时内增加 CD1 小鼠肿瘤组织中有丝分裂细胞（pH3 阳性细胞）的数量。[1]
别名	KIF18A 抑制剂 3

化学信息

分子量	574.76
分子式	C₂₈H₃₈N₄O₅S₂
CAS No.	2600577-49-7
Smiles	O=C(NC1=CC=CC(=C1)S(=O)(=O)NC(C)(C)C)C2=CC=C(C=C2N3CCC4(CC3)CC4)NS(=O)(=O)C5(C)CC5
颜色	Yellow
物理性状	Solid

储存&溶解度

存储

keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 80 mg/mL (139.19 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.7399 mL	8.6993 mL	17.3986 mL	86.9928 mL
5 mM	0.3480 mL	1.7399 mL	3.4797 mL	17.3986 mL
10 mM	0.1740 mL	0.8699 mL	1.7399 mL	8.6993 mL
20 mM	0.0870 mL	0.4350 mL	0.8699 mL	4.3496 mL
50 mM	0.0348 mL	0.1740 mL	0.3480 mL	1.7399 mL
100 mM	0.0174 mL	0.0870 mL	0.1740 mL	0.8699 mL

体内实验配液计算器