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Anti-Coagulation Factor II Antibody (8M286)
还可以产品编号 TMAY-03244
Anti-Coagulation Factor II Antibody (8M286) 是一种 Rabbit 抗体，靶向 Coagulation Factor II。Anti-Coagulation Factor II Antibody (8M286) 可用于 ELISA。
Anti-Coagulation Factor II Antibody (8M286)
Anti-Coagulation Factor II Antibody (8M286)
还可以产品编号 TMAY-03244
Anti-Coagulation Factor II Antibody (8M286) 是一种 Rabbit 抗体，靶向 Coagulation Factor II。Anti-Coagulation Factor II Antibody (8M286) 可用于 ELISA。
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偶联与修饰
抗原信息
| 产品描述 | Anti-Coagulation Factor II Antibody (8M286) is a Rabbit antibody targeting Coagulation Factor II. Anti-Coagulation Factor II Antibody (8M286) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 8M286 |
| 交叉反应 | Mouse |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Coagulation Factor II / F2 (rM Coagulation Factor II / F2; TMPY-01791; NP_034298.1; Met1-Gly618). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Coagulation Factor II Protein (FII, F2 Protein or Prothrombin) is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. Coagulation Factor II Protein (FII, F2 Protein) also plays a role in maintaining vascular integrity during development and postnatal life. Prothrombin / Coagulation Factor II is activated on the surface of a phospholipid membrane that binds the amino end of prothrombin / Coagulation Factor II and factor Va and Xa in Ca-dependent interactions; factor Xa removes the activation peptide and cleaves the remaining part into light and heavy chains. The activation process starts slowly because factor V itself has to be activated by the initial, small amounts of thrombin. Prothrombin / Coagulation Factor II is expressed by the liver and secreted in plasma. Defects in prothrombin / Coagulation Factor II are the cause of factor II deficiency (FA2D). It is very rare blood coagulation disorder characterized by mucocutaneous bleeding symptoms. The severity of the bleeding manifestations correlates with blood factor II levels. Defects in Coagulation Factor II are also a cause of susceptibility to thrombosis. It is a multifactorial disorder of hemostasis characterized by abnormal platelet aggregation in response to various agents and recurrent thrombi formation. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Mouse Coagulation Factor II / F2 protein (TMPY-01791) |
| 抗原种属 | Mouse |
| 研究领域 | Serine Proteases and Regulators |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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