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Anti-Synaptotagmin 1/SYT1 Polyclonal Antibody 2

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货号 TMAB-13320

Anti-Synaptotagmin 1/SYT1 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Synaptotagmin 1/SYT1。Anti-Synaptotagmin 1/SYT1 Polyclonal Antibody 2 可用于 WB。

Anti-Synaptotagmin 1/SYT1 Polyclonal Antibody 2

Anti-Synaptotagmin 1/SYT1 Polyclonal Antibody 2

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Rating icon 还可以
货号 TMAB-13320

Anti-Synaptotagmin 1/SYT1 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Synaptotagmin 1/SYT1。Anti-Synaptotagmin 1/SYT1 Polyclonal Antibody 2 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
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100 μL
¥ 1,960
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200 μL
¥ 2,785
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产品介绍

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产品描述
Anti-Synaptotagmin 1/SYT1 Polyclonal Antibody 2 is a Rabbit antibody targeting Synaptotagmin 1/SYT1. Anti-Synaptotagmin 1/SYT1 Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Single-pass membrane protein. Cytoplasm. Note=Synaptic vesicles and chromaffin granules.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin participates in triggering neurotransmitter release at the synapse. The first C2 domain mediates Ca(2+)-dependent phospholipid binding. The second C2 domain mediates interaction with Stonin 2. Synaptotagmin may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Synaptotagmin 1/SYT1
抗原种属
Human
基因名称
SYT1
基因ID
6857
蛋白名称
Synaptotagmin-1
Uniprot ID
P21579
功能
May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.
化学信息
分子量Theoretical: 48 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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