Anti-CD6 Antibody (5C343)

Name: Anti-CD6 Antibody (5C343)
Brand: TargetMol
SKU: TMAY-03814
Rating: 4.5 (1 reviews)

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产品编号 TMAY-03814

别名 TP120, CD6 molecule

Anti-CD6 Antibody (5C343) 是一种 Mouse 抗体，靶向 CD6。Anti-CD6 Antibody (5C343) 可用于 ELISA,IHC-P。

Anti-CD6 Antibody (5C343)

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产品编号 TMAY-03814 别名 TP120, CD6 molecule

Anti-CD6 Antibody (5C343) 是一种 Mouse 抗体，靶向 CD6。Anti-CD6 Antibody (5C343) 可用于 ELISA,IHC-P。

规格	价格	库存	数量
100 μL	¥ 1,694	5日内发货

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生物活性

产品描述	Anti-CD6 Antibody (5C343) is a Mouse antibody targeting CD6. Anti-CD6 Antibody (5C343) can be used in ELISA,IHC-P.
别名	TP120, CD6 molecule
Ig Type	Mouse IgG1
克隆号	5C343
交叉反应	Rat
特异性	Rat CD6 No cross-reactivity in ELISA with Human cell lysate (293 cell line)
验证活性	1. Immunochemical staining of rat CD6 in rat thymus with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of rat CD6 in rat spleen with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections).
应用	ELISA IHC-P
推荐剂量	ELISA: 1:1000-1:2000; IHC-P: 1:50-1:200
抗体种类	Monoclonal
宿主来源	Mouse
构建方式	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat CD6 / Cluster of Differentiation 6 (TMPY-03731; Q812A4; Met1-Asn396).
纯化方式	Protein A
性状	Liquid
缓冲液	0.2 μm filtered solution in PBS
研究背景	T-cell differentiation antigen CD6, also known as TP12 and CD6, is a single-pass type I membrane protein which contains threeSRCR domains. CD6 / TP12 is a cell surface glycoprotein expressed primarily on T cells, it may function as a costimulatory molecule and may play a role in autoreactive immune responses. CD6 / TP12 is expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain. CD6 ligand termed CD166 (previously known as activated leukocyte cell adhesion molecule, ALCAM ) has been identified and shown to be expressed on activated T cells, B cells, thymic epithelium, keratinocytes, and in rheumatoid arthritis synovial tissue. CD6 / TP12 binds to activated leukocyte cell adhesion molecule ( CD166 ), and is considered as a costimulatory molecule involved in lymphocyte activation and thymocyte development. CD6 / TP12 partially associates with the TCR / CD3 complex and colocalizes with it at the center of the mature immunological synapse (IS) on T lymphocytes. During thymic development CD6-dependent signals may contribute both to thymocyte survival, and to the overall functional avidity of selection in both man and mouse.

偶联与修饰

偶联	Unconjugated

抗原信息

免疫原	Recombinant Protein: Rat CD6 / Cluster of Differentiation 6 protein (TMPY-03731)
抗原种属	Rat
研究领域	ITIM/ITAM Immunoreceptors and Related Molecules

存储&运输

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式	Shipping with blue ice.