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Anti-IL-T4 Antibody-APC (5V475)
还可以产品编号 TMAY-02690A
Anti-IL-T4 Antibody-APC (5V475) 是一种 APC-conjugated Mouse 抗体，靶向 IL-T4。Anti-IL-T4 Antibody-APC (5V475) 可用于 FCM。
Anti-IL-T4 Antibody-APC (5V475)
Anti-IL-T4 Antibody-APC (5V475)
还可以产品编号 TMAY-02690A
Anti-IL-T4 Antibody-APC (5V475) 是一种 APC-conjugated Mouse 抗体，靶向 IL-T4。Anti-IL-T4 Antibody-APC (5V475) 可用于 FCM。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-IL-T4 Antibody-APC (5V475) is a APC-conjugated Mouse antibody targeting IL-T4. Anti-IL-T4 Antibody-APC (5V475) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG2b |
| 克隆号 | 5V475 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human LILRB2(CD85d) expression on human whole blood monocytes. Cells were stained with APC-conjugated anti-Human LILRB2(CD85d). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | 5 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human LILRB2/ILT4/LIR-2 (rh LILRB2/ILT4/LIR-2; TMPY-03284; AAH36827.1; Met1-Val461) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | ILT4, also known as LILRB2, is a member of the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). ILT4 gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. Multiple transcript variants encoding different isoforms have been found for the ILT4 gene. ILT4 is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. |
| 偶联 | APC |
| 其他可选修饰符 | Unconjugated/FITC/PE |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human LILRB2/ILT4/LIR-2 Protein (TMPY-03284) |
| 抗原种属 | Human |
| 研究领域 | ITIM/ITAM Immunoreceptors and Related Molecules |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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