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Anti-CX3CL1/Fractalkine Antibody (8F783)
还可以产品编号 TMAY-01043
Anti-CX3CL1/Fractalkine Antibody (8F783) 是一种 Rabbit 抗体，靶向 CX3CL1/Fractalkine。Anti-CX3CL1/Fractalkine Antibody (8F783) 可用于 ELISA,ELISA(Det),IHC-P。
Anti-CX3CL1/Fractalkine Antibody (8F783)
Anti-CX3CL1/Fractalkine Antibody (8F783)
还可以产品编号 TMAY-01043
Anti-CX3CL1/Fractalkine Antibody (8F783) 是一种 Rabbit 抗体，靶向 CX3CL1/Fractalkine。Anti-CX3CL1/Fractalkine Antibody (8F783) 可用于 ELISA,ELISA(Det),IHC-P。
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抗原信息
| 产品描述 | Anti-CX3CL1/Fractalkine Antibody (8F783) is a Rabbit antibody targeting CX3CL1/Fractalkine. Anti-CX3CL1/Fractalkine Antibody (8F783) can be used in ELISA,ELISA(Det),IHC-P. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 8F783 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunochemical staining of human CX3CL1 in human pancreas with rabbit monoclonal antibody (1:100, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human CX3CL1 in human kidney with rabbit monoclonal antibody (1:100, formalin-fixed paraffin embedded sections). |
| 应用 | ELISA,ELISA(Det),IHC-P |
| 推荐剂量 | ELISA: 1:5000-1:10000; IHC-P: 1:50-1:200; ELISA(Det): 1:1000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human Fractalkine / CX3CL1 (rh Fractalkine / CX3CL1; TMPY-00737; NP_002987.1; Met 1-Arg 339). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Fractalkine or Chemokine (C-X3-C motif) ligand 1 (CX3CL1) is a member of the CX3C chemokine family. Fractalkine / CX3CL1 is a unique chemokine that functions not only as a chemoattractant but also as an adhesion molecule and is expressed on endothelial cells activated by proinflammatory cytokines, such as interferon-gamma and tumor necrosis factor-alpha. Fractalkine/CX3CL1 is expressed in a membrane-bound form on activated endothelial cells and mediates attachment and firm adhesion of T cells, monocytes and NK cells. Fractalkine / CX3CL1 is associated with dendritic cells (DC) in epidermis and lymphoid organs. The fractalkine receptor, CX3CR1, is expressed on cytotoxic effector lymphocytes, including natural killer (NK) cells and cytotoxic T lymphocytes, which contain high levels of intracellular perforin and granzyme B, and on macrophages. Soluble fractalkine causes migration of NK cells, cytotoxic T lymphocytes, and macrophages, whereas the membrane-bound form captures and enhances the subsequent migration of these cells in response to secondary stimulation with other chemokines. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | HRP |
| 可提供抗体种类 | 2 |
| 免疫原 | Recombinant Human Fractalkine / CX3CL1 protein (TMPY-00737) |
| 抗原种属 | Human |
| 研究领域 | Neuroinflammation |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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