Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyrosine phosphates on the surface of the magnetic nanoparticle and enable the magnetic nanoparticles to adhere selectively to the cancer cells, such as HeLa cells. Placental alkaline phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
50 μg | ¥ 3,820 | 现货 | ||
100 μg | ¥ 6,750 | 5日内发货 | ||
200 μg | ¥ 11,900 | 5日内发货 | ||
500 μg | ¥ 25,140 | 5日内发货 |
生物活性 | Testing in progress |
产品描述 | Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyrosine phosphates on the surface of the magnetic nanoparticle and enable the magnetic nanoparticles to adhere selectively to the cancer cells, such as HeLa cells. Placental alkaline phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta. |
种属 | Human |
表达系统 | Yeast |
标签 | His |
蛋白编号 | AAH09647.1 |
别名 | ALPI, PALP, PLAP, PLAP-1, alkaline phosphatase, placental, IAP, ALP |
蛋白构建 | A DNA sequence encoding human ALPP (AAH09647.1) (Ile23-Asp506) was expressed with a polyhistidine tag at the C-terminus. |
蛋白纯度 |
> 80 % as determined by SDS-PAGE
|
分子量 | 54.1 kDa (predicted) |
内毒素 | Please contact us for more information. |
缓冲液 | Supplied as sterile 50 mM Tris-Acetate, 1 mM EDTA, 20 % glycerol, pH 7.5. Please contact us for any concerns or special requirements. Please refer to the specific buffer information in the hard copy of CoA. |
复溶方法 | A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information. |
存储 |
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
运输方式 |
Solution. It is shipped out with blue ice. |
研究背景 | Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyrosine phosphates on the surface of the magnetic nanoparticle and enable the magnetic nanoparticles to adhere selectively to the cancer cells, such as HeLa cells. Placental alkaline phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta. |
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Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His) ALPI PLAP1 PLAP 1 PALP PLAP PLAP-1 alkaline phosphatase, placental IAP ALP recombinant recombinant-proteins proteins protein