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Anti-Caspase-1 P10 Polyclonal Antibody 3

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货号 TMAB-03649

Anti-Caspase-1 P10 Polyclonal Antibody 3 是一种 Rabbit 抗体，靶向 Caspase-1 P10。Anti-Caspase-1 P10 Polyclonal Antibody 3 可用于 WB,FCM。

Anti-Caspase-1 P10 Polyclonal Antibody 3

Anti-Caspase-1 P10 Polyclonal Antibody 3

一键复制产品信息
Rating icon 还可以
货号 TMAB-03649

Anti-Caspase-1 P10 Polyclonal Antibody 3 是一种 Rabbit 抗体，靶向 Caspase-1 P10。Anti-Caspase-1 P10 Polyclonal Antibody 3 可用于 WB,FCM。

规格价格库存数量
50 μL
¥ 1,160
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100 μL
¥ 1,970
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200 μL
¥ 2,795
5日内发货
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产品介绍

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产品描述
Anti-Caspase-1 P10 Polyclonal Antibody 3 is a Rabbit antibody targeting Caspase-1 P10. Anti-Caspase-1 P10 Polyclonal Antibody 3 can be used in WB,FCM.
Ig Type
IgG
反应种属
Human,Mouse
应用WBFCM
推荐剂量
WB: 1:500-2000; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
组织特异性Expressed in larger amounts in spleen and lung. Detected in liver, heart, small intestine, colon, thymus, prostate, skeletal muscle, peripheral blood leukocytes, kidney and testis. No expression in the brain.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing of this gene results in five transcript variants encoding distinct isoforms. [provided by RefSeq].
抗原信息
免疫原
KLH conjugated synthetic peptide: human Caspase-1 P10
抗原种属
Human
基因名称
CASP1
基因ID
834
蛋白名称
Caspase-1
Uniprot ID
P29466
功能
Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
化学信息
分子量Theoretical: 10/45 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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