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顶部生物活性储存和溶解信息计算器

Anti-Phospho-GRK2 (Ser29) Polyclonal Antibody 2

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产品编号 TMAB-10753

Anti-Phospho-GRK2 (Ser29) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-GRK2 (Ser29)。Anti-Phospho-GRK2 (Ser29) Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

Anti-Phospho-GRK2 (Ser29) Polyclonal Antibody 2

Anti-Phospho-GRK2 (Ser29) Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
产品编号 TMAB-10753

Anti-Phospho-GRK2 (Ser29) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-GRK2 (Ser29)。Anti-Phospho-GRK2 (Ser29) Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-GRK2 (Ser29) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-GRK2 (Ser29). Anti-Phospho-GRK2 (Ser29) Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
交叉反应
Rat (predicted:Human,Mouse,Dog,Pig,Cow,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
组织特异性Expressed in peripheral blood leukocytes.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq].
抗原信息
免疫原
KLH conjugated synthesised phosphopeptide: human GRK2 around the phosphorylation site of Ser29
抗原种属
Human
基因名称
GRK2
基因ID
156
蛋白名称
beta-adrenergic receptor kinase 1
Uniprot ID
P25098
功能
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.
化学信息
分子量Theoretical: 76 kDa.
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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