Name: DNAM-1/CD226 Protein, Human, Recombinant (His & Avi)
Brand: TargetMol
SKU: TMPK-00229
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 246

6-8日内发货

10 μg

¥ 383

6-8日内发货

20 μg

¥ 616

5日内发货

50 μg

¥ 1,190

5日内发货

100 μg

¥ 1,990

5日内发货

200 μg

¥ 3,590

5日内发货

500 μg

¥ 8,000

5日内发货

生物活性

产品描述	DNAX accessory molecule-1 (DNAM-1), also known as CD226, is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily.DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2. DNAM-1/CD226 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 28.9 kDa and the accession number is Q15762.
生物活性	1. Immobilized Human DNAM-1, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Human CD155, mFc Tag with the EC50 of 0.24μg/ml determined by ELISA (QC Test). 2. Human CD155, hFc Tag captured on Protein A chip, can bind Human DNAM-1, His Tag with an affinity constant of 0.22μM as determined in a SPR assay.
研究背景	DNAX accessory molecule-1 (DNAM-1), also known as CD226, is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily.DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2.
种属	Human
表达系统	HEK293 Cells
标签	C-His-Avi
蛋白编号	Q15762
蛋白构建	Glu19-Asn247
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by SEC-HPLC
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	TLiSA1, PTA1, DNAM1, CD226 molecule, CD226
内毒素	< 1 EU/μg by the LAL method.

化学信息

分子量	28.9 kDa (predicted). Due to glycosylation, the protein migrates to 45-70 kDa based on Tris-Bis PAGE result.

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

DNAM-1/CD226 Protein, Human, Recombinant (His & Avi)

DNAM-1/CD226 Protein, Human, Recombinant (His & Avi)

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