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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-INO80 Polyclonal Antibody

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货号 TMAB-07714

Anti-INO80 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 INO80。Anti-INO80 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-INO80 Polyclonal Antibody

Anti-INO80 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-07714

Anti-INO80 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 INO80。Anti-INO80 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-INO80 Polyclonal Antibody is a Rabbit antibody targeting INO80. Anti-INO80 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Dog,Cow,Horse,Rabbit,Monkey, Macaque Monkey)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Colocalizes with PCNA at replication forks during S-phase. Recruited to DNA damage sites in a ACTR8-dependent manner.
组织特异性According to PubMed:10574462, widely expressed. According to PubMed:16298340, specifically expressed in brain, liver and pancreas.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a subunit of the chromatin remodeling complex, which is classified into subfamilies depending on sequence features apart from the conserved ATPase domain. This protein is the catalytic ATPase subunit of the INO80 chromatin remodeling complex, which is characterized by a DNA-binding domain. This protein is proposed to bind DNA and be recruited by the YY1 transcription factor to activate certain genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
抗原信息
免疫原
KLH conjugated synthetic peptide: human INO80
抗原种属
Human
基因名称
INO80
基因ID
54617
蛋白名称
Chromatin-remodeling ATPase INO80
Uniprot ID
Q9ULG1
功能
DNA helicase and probable main scaffold component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair; according to PubMed:20687897 the contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation. Recruited by YY1 to YY1-activated genes, where it acts as an essential coactivator. Binds DNA. In vitro, has double stranded DNA-dependent ATPase activity. Involved in UV-damage excision repair, DNA replication and chromosome segregation during normal cell division cycle.
化学信息
分子量Theoretical: 177 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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