购物车
全部删除
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-SOCS1 Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
货号 TMAB-13017

Anti-SOCS1 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 SOCS1。Anti-SOCS1 Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

Anti-SOCS1 Polyclonal Antibody 2

Anti-SOCS1 Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
货号 TMAB-13017

Anti-SOCS1 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 SOCS1。Anti-SOCS1 Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
大包装 & 定制
加入购物车
TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
资源下载:
产品操作手册

产品介绍

生物活性
产品描述
Anti-SOCS1 Polyclonal Antibody 2 is a Rabbit antibody targeting SOCS1. Anti-SOCS1 Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Dog,Pig,Cow,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasmic vesicle. Note=Detected in perinuclear cytoplasmic vesicles upon interaction with FGFR3.
组织特异性Expressed in all tissues with high expression in spleen, small intestine and peripheral blood leukocytes.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS1 is involved in negative regulation of cytokines that signal through the JAK/STAT3 pathway. Through binding to JAKs, inhibits their kinase activity. In vitro, also suppresses Tec protein-tyrosine activity (By similarity). Appears to be a major regulator of signaling by interleukin 6 (IL6) and leukemia inhibitory factor(LIF). Regulates interferon-gamma mediated sensory neuron survival. Implicated, through SOCS box binding, in ubiquitin-dependent protein degradation. High expression in thymus. Lower expression in lung and spleen.
抗原信息
免疫原
KLH conjugated synthetic peptide: human SOCS1
抗原种属
Human
基因名称
SOCS1
基因ID
8651
蛋白名称
Suppressor of cytokine signaling 1
Uniprot ID
O15524
功能
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS1 is involved in negative regulation of cytokines that signal through the JAK/STAT3 pathway. Through binding to JAKs, inhibits their kinase activity. In vitro, also suppresses Tec protein-tyrosine activity. Appears to be a major regulator of signaling by interleukin 6 (IL6) and leukemia inhibitory factor (LIF). Regulates interferon-gamma mediated sensory neuron survival (By similarity). Probable substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to recognize JAK2. SOCS1 appears to be a negative regulator in IGF1R signaling pathway.
化学信息
分子量Theoretical: 23 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
Related Tags: buy Anti-SOCS1 Polyclonal Antibody 2 | purchase Anti-SOCS1 Polyclonal Antibody 2 | Anti-SOCS1 Polyclonal Antibody 2 cost | order Anti-SOCS1 Polyclonal Antibody 2 | Anti-SOCS1 Polyclonal Antibody 2 molecular weight