购物车
全部删除
您的购物车当前为空
Anti-MYLK3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 MYLK3。Anti-MYLK3 Polyclonal Antibody 可用于 WB。
Anti-MYLK3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 MYLK3。Anti-MYLK3 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
| 产品描述 | Anti-MYLK3 Polyclonal Antibody is a Rabbit antibody targeting MYLK3. Anti-MYLK3 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Mouse (predicted:Human,Rat,Dog,Cow,Horse,Rabbit,Sheep) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. |
| 组织特异性 | May play a role in smooth muscle contraction. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The Ca2+/calmodulin-dependent protein kinases (CaM kinases) are a structurally related subfamily of serine/threonine kinases that includes CaMKI, CaMKII, CaMKIV and Myosin light chain kinases (MYLKs, also designated MLCKs). The MYLK kinases phosphorylate Myosin regulatory light chains to catalyze Myosin interaction with Actin filaments, resulting in contractile activity. MYLK3 (Myosin light chain kinase 3) is a 795 amino acid cardiac-specific protein that contains one protein kinase domain and belongs to the protein kinase superfamily. Like other MYLK kinases, MYLK3 is thought to play a role in smooth muscle contraction, specifically using magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of Myosin light chain proteins. Additionally, MYLK3 may regulate sarcomere assembly in heart tissue, possibly mediating proper heart function. |
| 免疫原 | KLH conjugated synthetic peptide: human MYLK3 |
| 抗原种属 | Human |
| 基因名称 | MYLK3 |
| 基因ID | |
| 蛋白名称 | Myosin light chain kinase 3 |
| Uniprot ID | |
| 功能 | Kinase that phosphorylates MYL2 in vitro. Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility (By similarity). |
| 分子量 | Theoretical: 98 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |