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Anti-MYLK3 Polyclonal Antibody

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货号 TMAB-09161

Anti-MYLK3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 MYLK3。Anti-MYLK3 Polyclonal Antibody 可用于 WB。

Anti-MYLK3 Polyclonal Antibody

Anti-MYLK3 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-09161

Anti-MYLK3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 MYLK3。Anti-MYLK3 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-MYLK3 Polyclonal Antibody is a Rabbit antibody targeting MYLK3. Anti-MYLK3 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
组织特异性May play a role in smooth muscle contraction.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The Ca2+/calmodulin-dependent protein kinases (CaM kinases) are a structurally related subfamily of serine/threonine kinases that includes CaMKI, CaMKII, CaMKIV and Myosin light chain kinases (MYLKs, also designated MLCKs). The MYLK kinases phosphorylate Myosin regulatory light chains to catalyze Myosin interaction with Actin filaments, resulting in contractile activity. MYLK3 (Myosin light chain kinase 3) is a 795 amino acid cardiac-specific protein that contains one protein kinase domain and belongs to the protein kinase superfamily. Like other MYLK kinases, MYLK3 is thought to play a role in smooth muscle contraction, specifically using magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of Myosin light chain proteins. Additionally, MYLK3 may regulate sarcomere assembly in heart tissue, possibly mediating proper heart function.
抗原信息
免疫原
KLH conjugated synthetic peptide: human MYLK3
抗原种属
Human
基因名称
MYLK3
基因ID
蛋白名称
Myosin light chain kinase 3
Uniprot ID
功能
Kinase that phosphorylates MYL2 in vitro. Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility (By similarity).
化学信息
分子量Theoretical: 98 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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