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GITR/TNFRSF18 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.3 kDa and the accession number is Q9Y5U5-1.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 μg | ¥ 336 | 6-8日内发货 | |
10 μg | ¥ 538 | 6-8日内发货 | |
20 μg | ¥ 858 | 5日内发货 | |
50 μg | ¥ 1,700 | 5日内发货 | |
100 μg | ¥ 3,380 | 5日内发货 | |
200 μg | ¥ 5,150 | 5日内发货 | |
500 μg | ¥ 11,200 | 5日内发货 | |
1 mg | ¥ 23,800 | 5日内发货 |
生物活性 | Immobilized Human GITR Ligand Trimer, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Human GITR, hFc Tag with the EC50 of 0.44 μg/ml determined by ELISA. |
产品描述 | GITR/TNFRSF18 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.3 kDa and the accession number is Q9Y5U5-1. |
种属 | Human |
表达系统 | HEK293 Cells |
标签 | C-hFc |
蛋白编号 | Q9Y5U5-1 |
别名 | tumor necrosis factor receptor superfamily, member 18,GITR-D,GITR,CD357,AITR |
蛋白构建 | Gln26-Glu161 |
蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
分子量 | 41.3 kDa (Predicted); 45-55 kDa (Due to glycosylation) |
内毒素 | Less than 1EU per μg by the LAL method. |
缓冲液 | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
存储 | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
研究背景 | GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. |