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GITR/TNFRSF18 Protein, Human, Recombinant (hFc)

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货号 TMPY-04265

别名 tumor necrosis factor receptor superfamily, member 18, GITR-D, GITR, CD357, AITR

GITR/TNFRSF18 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.3 kDa and the accession number is Q9Y5U5-1.

GITR/TNFRSF18 Protein, Human, Recombinant (hFc)

GITR/TNFRSF18 Protein, Human, Recombinant (hFc)

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货号 TMPY-04265 别名 tumor necrosis factor receptor superfamily, member 18, GITR-D, GITR, CD357, AITR

GITR/TNFRSF18 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.3 kDa and the accession number is Q9Y5U5-1.

规格价格库存数量
5 μg
¥ 336
6-8日内发货
10 μg
¥ 538
6-8日内发货
20 μg
¥ 858
5日内发货
50 μg
¥ 1,700
5日内发货
100 μg
¥ 3,380
5日内发货
200 μg
¥ 5,150
5日内发货
500 μg
¥ 11,200
5日内发货
1 mg
¥ 23,800
5日内发货
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产品介绍


生物活性
产品描述
GITR/TNFRSF18 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.3 kDa and the accession number is Q9Y5U5-1.
生物活性
Immobilized Human GITR Ligand Trimer, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Human GITR, hFc Tag with the EC50 of 0.44 μg/ml determined by ELISA.
研究背景
GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
种属
Human
表达系统
HEK293 Cells
标签C-hFc
蛋白编号Q9Y5U5-1
蛋白构建Gln26-Glu161
蛋白纯度
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状Lyophilized powder
缓冲液Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名tumor necrosis factor receptor superfamily, member 18, GITR-D, GITR, CD357, AITR
内毒素Less than 1EU per μg by the LAL method.
化学信息
分子量41.3 kDa (Predicted); 45-55 kDa (Due to glycosylation)
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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